7-METHOXY-2H-CHROMENE-3-CARBOXYLIC ACID METHYL ESTER

Base Information

• Chemical Name: 7-METHOXY-2H-CHROMENE-3-CARBOXYLIC ACID METHYL ESTER
• CAS No.: 86236-08-0
• Molecular Formula: C₁₂H₁₂O₄
• Molecular Weight: 220.225
• Hs Code.: 2918990090
• Mol file: 86236-08-0.mol

Synonyms:7-METHOXY-2H-CHROMENE-3-CARBOXYLIC ACID METHYL ESTER

Chemical Property of 7-METHOXY-2H-CHROMENE-3-CARBOXYLIC ACID METHYL ESTER

Chemical Property:

• PSA: 44.76000
• LogP: 1.64400

Purity/Quality:

97% ^*data from raw suppliers

7-Methoxy-2H-chromene-3-carboxylicacidmethylester 96% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 7-METHOXY-2H-CHROMENE-3-CARBOXYLIC ACID METHYL ESTER

There total 1 articles about 7-METHOXY-2H-CHROMENE-3-CARBOXYLIC ACID METHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.5%

acide methoxy-7 2H chromene carboxylique-3 (57543-60-9) + dimethyl sulfate (77-78-1) → carbomethoxy-3 methoxy-7 2H chromene (86236-08-0)

Guidance literature:

With potassium carbonate; In acetone; for 4h; Heating;

Reference yield:

carbomethoxy-3 methoxy-7 2H chromene (86236-08-0) → pyrano[3,2-g][1]benzopyran-2-one (6054-09-7)

Guidance literature:

Multi-step reaction with 7 steps

1: 50.5 percent / TiCl₄ / CH₂Cl₂ / 1 h / Ambient temperature

2: 83 percent / 10percent aq. K₂CO₃ / Heating

3: 77 percent / Cu powder / quinoline / Heating

4: 59 percent / BCl₃ / CH₂Cl₂ / 1 h / 0 °C

5: 92 percent / piperidine / ethanol / 20 h / Heating

6: 82 percent / HCl / acetic acid / 2 h / Heating

7: 52.5 percent / Cu powder / quinoline / Heating

With piperidine; hydrogenchloride; boron trichloride; titanium tetrachloride; copper; potassium carbonate; In quinoline; ethanol; dichloromethane; acetic acid;

Reference yield:

carbomethoxy-3 methoxy-7 2H chromene (86236-08-0) → 2-Oxo-2H,8H-pyrano[3,2-g]chromene-3-carboxylic acid ethyl ester (86116-44-1)

Guidance literature:

Multi-step reaction with 5 steps

1: 50.5 percent / TiCl₄ / CH₂Cl₂ / 1 h / Ambient temperature

2: 83 percent / 10percent aq. K₂CO₃ / Heating

3: 77 percent / Cu powder / quinoline / Heating

4: 59 percent / BCl₃ / CH₂Cl₂ / 1 h / 0 °C

5: 92 percent / piperidine / ethanol / 20 h / Heating

With piperidine; boron trichloride; titanium tetrachloride; copper; potassium carbonate; In quinoline; ethanol; dichloromethane;

upstream raw materials:

acide methoxy-7 2H chromene carboxylique-3

dimethyl sulfate

Downstream raw materials:

pyrano[3,2-g][1]benzopyran-2-one

2-Oxo-2H,8H-pyrano[3,2-g]chromene-3-carboxylic acid ethyl ester