(±)-2-[(4-fluorobenzyl)oxy]tetrahydropyran

Base Information

Chemical Name:(±)-2-[(4-fluorobenzyl)oxy]tetrahydropyran
CAS No.:18539-44-1
Molecular Formula:C₁₂H₁₅FO₂
Molecular Weight:210.248
Hs Code.:

Synonyms:(±)-2-[(4-fluorobenzyl)oxy]tetrahydropyran

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (±)-2-[(4-fluorobenzyl)oxy]tetrahydropyran

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Technology Process of (±)-2-[(4-fluorobenzyl)oxy]tetrahydropyran

There total 4 articles about (±)-2-[(4-fluorobenzyl)oxy]tetrahydropyran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 110-87-2
3,4-dihydro-2H-pyran

: 459-56-3
4-fluorobenzylic alcohol

: 18539-44-1
(±)-2-[(4-fluorobenzyl)oxy]tetrahydropyran

Guidance literature:: With 1,4-diazabicyclo[2.2.2]octane tribromide supported on magnetic Fe₃O₄ nanoparticles; In dichloromethane; at 20 ℃; for 5h;
DOI:10.1039/c7nj00479f

Reference yield: 89.0%

: 110-87-2
3,4-dihydro-2H-pyran

: 14629-55-1
(4-fluorobenzyloxy)trimethylsilane

: 18539-44-1
(±)-2-[(4-fluorobenzyl)oxy]tetrahydropyran

Guidance literature:: With [K*18-crown-6]Br₃; water; In acetonitrile; at 20 ℃; for 0.25h;
DOI:10.1080/00304948.2019.1586430

Reference yield:

: 142-68-7
TETRAHYDROPYRANE

: 459-56-3
4-fluorobenzylic alcohol

: 18539-44-1
(±)-2-[(4-fluorobenzyl)oxy]tetrahydropyran

Guidance literature:: TETRAHYDROPYRANE; With bis(cyclopentadienyl)titanium dichloride; manganese; at 20 ℃; for 0.25h; Inert atmosphere;

4-fluorobenzylic alcohol; With Bromoform; at 20 ℃; for 16h; Inert atmosphere;
DOI:10.1002/ejoc.201500869