2-amino-2-(3,4,5-trimethoxyphenyl)acetic Acid

Base Information

Chemical Name:2-amino-2-(3,4,5-trimethoxyphenyl)acetic Acid
CAS No.:86053-97-6
Molecular Formula:C₁₁H₁₅NO₅
Molecular Weight:241.244
Hs Code.:2922509090
DSSTox Substance ID:DTXSID50408310
Nikkaji Number:J1.289.634D
Mol file:86053-97-6.mol

Synonyms:86053-97-6;2-amino-2-(3,4,5-trimethoxyphenyl)acetic Acid;AMINO-(3,4,5-TRIMETHOXY-PHENYL)-ACETIC ACID;Benzeneacetic acid, a-amino-3,4,5-trimethoxy-;SCHEMBL23201028;DTXSID50408310;58716-91-9;AKOS000180479;AKOS016045353;AB07064;AB33208;AB33209;BB 0249656;EN300-1838330;(2R)-2-amino-2-(3,4,5-trimethoxyphenyl)acetic acid;(2S)-2-amino-2-(3,4,5-trimethoxyphenyl)acetic acid

Suppliers and Price of 2-amino-2-(3,4,5-trimethoxyphenyl)acetic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
Amino-(3,4,5-trimethoxy-phenyl)-aceticacid 95
25g
$ 3117.00

American Custom Chemicals Corporation
2-AMINO-2-(3,4,5-TRIMETHOXYPHENYL)ACETIC ACID 95.00%
5MG
$ 497.63

Total 3 raw suppliers

Chemical Property of 2-amino-2-(3,4,5-trimethoxyphenyl)acetic Acid

Chemical Property:

PSA：91.01000
LogP:1.49710
XLogP3:-1.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:241.09502258
Heavy Atom Count:17
Complexity:246

Purity/Quality:

98%min ^*data from raw suppliers

Amino-(3,4,5-trimethoxy-phenyl)-aceticacid 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=CC(=C1OC)OC)C(C(=O)O)N

Technology Process of 2-amino-2-(3,4,5-trimethoxyphenyl)acetic Acid

There total 8 articles about 2-amino-2-(3,4,5-trimethoxyphenyl)acetic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 86-81-7
3,4,5-trimethoxy-benzaldehyde

: 86053-97-6
2-(3,4,5-trimethoxyphenyl)glycine

Guidance literature:: Multi-step reaction with 4 steps

1: Na₂S₂O₅ / methanol; H₂O / 2 h / 35 °C

2: 84 percent / aq. H₂O₂; K₂CO₃ / dimethylsulfoxide / 16.5 h / 21 - 35 °C

3: 92 percent / NaOH; H₂O / various solvent(s) / 3.5 h / Heating

4: hydrazine hydrate; NaOH / Pd/C / H₂O; various solvent(s) / 10 h / Heating

With sodium metabisulfite; sodium hydroxide; water; dihydrogen peroxide; potassium carbonate; hydrazine hydrate; palladium on activated charcoal; In methanol; water; dimethyl sulfoxide; 1: Addition / 2: Hydrolysis / 3: Hydrolysis / 4: Hydrogenolysis;
DOI:10.1080/00397910008087127

Reference yield:

: 271583-26-7
benzylamino-(3,4,5-trimethoxy-phenyl)-acetic acid

: 86053-97-6
2-(3,4,5-trimethoxyphenyl)glycine

Guidance literature:: With sodium hydroxide; hydrazine hydrate; palladium on activated charcoal; In water; for 10h; Heating;
DOI:10.1080/00397910008087127

Reference yield:

: 271583-64-3
benzylamino-(3,4,5-trimethoxy-phenyl)-acetonitrile

: 86053-97-6
2-(3,4,5-trimethoxyphenyl)glycine

Guidance literature:: Multi-step reaction with 3 steps

1: 84 percent / aq. H₂O₂; K₂CO₃ / dimethylsulfoxide / 16.5 h / 21 - 35 °C

2: 92 percent / NaOH; H₂O / various solvent(s) / 3.5 h / Heating

3: hydrazine hydrate; NaOH / Pd/C / H₂O; various solvent(s) / 10 h / Heating

With sodium hydroxide; water; dihydrogen peroxide; potassium carbonate; hydrazine hydrate; palladium on activated charcoal; In water; dimethyl sulfoxide; 1: Hydrolysis / 2: Hydrolysis / 3: Hydrogenolysis;
DOI:10.1080/00397910008087127