ethyl (2E)-3-{1-[2-chloro-4-(trifluoromethyl)benzyl]-3-(cyclopropylmethoxy)-1H-pyrazol-5-yl}acrylate

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Chemical Name:ethyl (2E)-3-{1-[2-chloro-4-(trifluoromethyl)benzyl]-3-(cyclopropylmethoxy)-1H-pyrazol-5-yl}acrylate
CAS No.:926296-22-2
Molecular Formula:C₂₀H₂₀ClF₃N₂O₃
Molecular Weight:428.839
Hs Code.:

Synonyms:ethyl (2E)-3-{1-[2-chloro-4-(trifluoromethyl)benzyl]-3-(cyclopropylmethoxy)-1H-pyrazol-5-yl}acrylate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of ethyl (2E)-3-{1-[2-chloro-4-(trifluoromethyl)benzyl]-3-(cyclopropylmethoxy)-1H-pyrazol-5-yl}acrylate

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Technology Process of ethyl (2E)-3-{1-[2-chloro-4-(trifluoromethyl)benzyl]-3-(cyclopropylmethoxy)-1H-pyrazol-5-yl}acrylate

There total 1 articles about ethyl (2E)-3-{1-[2-chloro-4-(trifluoromethyl)benzyl]-3-(cyclopropylmethoxy)-1H-pyrazol-5-yl}acrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 926296-21-1
ethyl (E)-3-{1-[2-chloro-4-(trifluoromethyl)benzyl]-3-hydroxy-1H-pyrazol-5-yl}propenoate

: 7051-34-5
cyclopropylcarbinyl bromide

: 926296-22-2
ethyl (2E)-3-{1-[2-chloro-4-(trifluoromethyl)benzyl]-3-(cyclopropylmethoxy)-1H-pyrazol-5-yl}acrylate

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 0 - 30 ℃; for 15h;

Reference yield: 94.0%

: 926296-22-2
ethyl (2E)-3-{1-[2-chloro-4-(trifluoromethyl)benzyl]-3-(cyclopropylmethoxy)-1H-pyrazol-5-yl}acrylate

: 926296-49-3
ethyl 3-[1-[2-chloro-4-(trifluoromethyl)benzyl]-3-(cyclopropylmethoxy)-1H-pyrazol-5-yl]propanoate

Guidance literature:: With hydrogen; 5%-palladium/activated carbon; In tetrahydrofuran; at 0 - 30 ℃;

Reference yield: 80.0%

: 926296-22-2
ethyl (2E)-3-{1-[2-chloro-4-(trifluoromethyl)benzyl]-3-(cyclopropylmethoxy)-1H-pyrazol-5-yl}acrylate

: (2E)-3-[1-[2-chloro-4-(trifluoromethyl)benzyl]-3-(cyclopropylmethoxy)-1H-pyrazol-5-yl]acrylic acid

Guidance literature:: ethyl (2E)-3-{1-[2-chloro-4-(trifluoromethyl)benzyl]-3-(cyclopropylmethoxy)-1H-pyrazol-5-yl}acrylate; With sodium hydroxide; ethanol; water; In tetrahydrofuran; at 50 ℃; for 1h;

With hydrogenchloride; In tetrahydrofuran; water;