C₂₆H₂₁BrN₂O₃

Base Information

• Chemical Name: C₂₆H₂₁BrN₂O₃
• CAS No.: 1338711-08-2
• Molecular Formula: C₂₆H₂₁BrN₂O₃
• Molecular Weight: 489.368
• Mol file: 1338711-08-2.mol

Synonyms:C₂₆H₂₁BrN₂O₃

Chemical Property of C₂₆H₂₁BrN₂O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₆H₂₁BrN₂O₃

There total 4 articles about C₂₆H₂₁BrN₂O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

p-methoxybenzyl chloride (824-94-2) + 2-(2-(2-bromo-1H-indol-3-yl)ethyl)isoindoline-1,3-dione (192182-46-0) → C26H21BrN2O3 (1338711-08-2)

Guidance literature:

2-(2-(2-bromo-1H-indol-3-yl)ethyl)isoindoline-1,3-dione; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 - 20 ℃;

p-methoxybenzyl chloride; In N,N-dimethyl-formamide; mineral oil; at 0 - 20 ℃; for 4h;

DOI:10.1021/ol202475r

Reference yield:

phthalic anhydride (85-44-9) → C26H21BrN2O3 (1338711-08-2)

Guidance literature:

Multi-step reaction with 3 steps

1.1: toluene / Reflux

2.1: pyridinium perbromide hydrobromide / tetrahydrofuran; chloroform / 2.33 h / -10 °C

3.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0 - 20 °C

3.2: 4 h / 0 - 20 °C

With pyridinium perbromide hydrobromide; sodium hydride; In tetrahydrofuran; chloroform; N,N-dimethyl-formamide; toluene; mineral oil;

DOI:10.1021/ol202475r

Reference yield:

tryptamine (61-54-1) → C26H21BrN2O3 (1338711-08-2)

Guidance literature:

Multi-step reaction with 3 steps

1.1: toluene / Reflux

2.1: pyridinium perbromide hydrobromide / tetrahydrofuran; chloroform / 2.33 h / -10 °C

3.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0 - 20 °C

3.2: 4 h / 0 - 20 °C

With pyridinium perbromide hydrobromide; sodium hydride; In tetrahydrofuran; chloroform; N,N-dimethyl-formamide; toluene; mineral oil;

DOI:10.1021/ol202475r

upstream raw materials:

phthalic anhydride

tryptamine

N-phthalimidotryptamine

p-methoxybenzyl chloride

Downstream raw materials:

C₃₅H₃₁N₃O₅S

C₃₅H₃₃N₃O₅S

C₃₅H₃₂N₆O₄S

C₃₅H₃₂N₄O₃S