the Schiff base of p-bromobenzaldehyde and ethyl glycinate

Base Information

• Chemical Name: the Schiff base of p-bromobenzaldehyde and ethyl glycinate
• CAS No.: 199532-82-6
• Molecular Formula: C₁₁H₁₂BrNO₂
• Molecular Weight: 270.126
• Mol file: 199532-82-6.mol

Synonyms:the Schiff base of p-bromobenzaldehyde and ethyl glycinate

Chemical Property of the Schiff base of p-bromobenzaldehyde and ethyl glycinate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of the Schiff base of p-bromobenzaldehyde and ethyl glycinate

There total 1 articles about the Schiff base of p-bromobenzaldehyde and ethyl glycinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

glycine ethyl ester hydrochloride (623-33-6) + 4-bromo-benzaldehyde (1122-91-4) → the Schiff base of p-bromobenzaldehyde and ethyl glycinate (199532-82-6)

Guidance literature:

DOI:10.1016/S0040-4039(00)02217-6

Reference yield: 99.0%

Phthalazinium dicyanomethanide 1,3-dipole (70704-69-7) + the Schiff base of p-bromobenzaldehyde and ethyl glycinate (199532-82-6) → (1S,3S,11bR)-ethyl 3-(4-bromophenyl)-4,4-dicyano-2,3,4,11b-tetrahydro-1H-pyrazino[2,1-a]phthalazine-1-carboxylate

Guidance literature:

With C₂₈H₂₈FeNOP; tetrakis(acetonitrile)copper(I) tetrafluoroborate; 1,8-diazabicyclo[5.4.0]undec-7-ene; In 1,2-dichloro-ethane; at -20 ℃; for 24h; stereoselective reaction; Inert atmosphere;

DOI:10.1021/ol503169d

Reference yield: 94.0%

N-phenyl-maleimide (941-69-5) + the Schiff base of p-bromobenzaldehyde and ethyl glycinate (199532-82-6) → ethyl (1S,3R,3aS,6aR)-4,6-dioxo-3-(p-bromophenyl)-5-phenyl-octahydropyrrole[3,4-c]pyrrole-1-carboxylate (1443277-99-3)

Guidance literature:

With C₃₂H₂₉FeN₂OP; silver(I) acetate; triethylamine; In toluene; at -20 ℃; for 12h; stereoselective reaction; Inert atmosphere;

DOI:10.1016/j.tetlet.2013.05.003

upstream raw materials:

glycine ethyl ester hydrochloride

4-bromo-benzaldehyde

Downstream raw materials:

ethyl 1-((4-bromobenzylidene)amino)cyclopent-3-ene-1-carboxylate

1-ethoxycarbonylmethyl-4,5-bis-(4-bromophenyl)-1H-imidazole-2-carboxylic acid ethyl ester

C₁₇H₂₀BrNO₆

ethyl (1S,3R,3aS,6aR)-4,6-dioxo-3-(p-bromophenyl)-5-phenyl-octahydropyrrole[3,4-c]pyrrole-1-carboxylate