3-(3-bromo-4,7-dichloroquinolin-6-yl)-N,N-dimethylbenzeneamine

Base Information

• Chemical Name: 3-(3-bromo-4,7-dichloroquinolin-6-yl)-N,N-dimethylbenzeneamine
• CAS No.: 1032816-47-9
• Molecular Formula: C₁₇H₁₃BrCl₂N₂
• Molecular Weight: 396.114
• Mol file: 1032816-47-9.mol

Synonyms:3-(3-bromo-4,7-dichloroquinolin-6-yl)-N,N-dimethylbenzeneamine

Chemical Property of 3-(3-bromo-4,7-dichloroquinolin-6-yl)-N,N-dimethylbenzeneamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(3-bromo-4,7-dichloroquinolin-6-yl)-N,N-dimethylbenzeneamine

There total 2 articles about 3-(3-bromo-4,7-dichloroquinolin-6-yl)-N,N-dimethylbenzeneamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

3-(N,N-dimethylamino)phenylboronic acid (178752-79-9) + 3-bromo-4,7-dichloro-6-iodoquinoline (1032816-46-8) → 3-(3-bromo-4,7-dichloroquinolin-6-yl)-N,N-dimethylbenzeneamine (1032816-47-9)

Guidance literature:

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; caesium carbonate; In tetrahydrofuran; at 90 ℃; for 0.25h; microwave irradiation;

DOI:10.1016/j.tetlet.2008.03.040

Reference yield:

3-(N,N-dimethylamino)phenylboronic acid (178752-79-9) + 3-bromo-4,7-dichloro-6-iodoquinoline (1032816-46-8) → 3-(3-bromo-4,7-dichloroquinolin-6-yl)-N,N-dimethylbenzeneamine (1032816-47-9) + C25H23Cl2N3

Guidance literature:

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; caesium carbonate; In tetrahydrofuran; at 120 ℃; for 0.166667h; microwave irradiation;

DOI:10.1016/j.tetlet.2008.03.040

Reference yield: 66.0%

3-(3-bromo-4,7-dichloroquinolin-6-yl)-N,N-dimethylbenzeneamine (1032816-47-9) + 4-methylphenylboronic acid (5720-05-8) → C24H20Cl2N2 (1032816-48-0)

Guidance literature:

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; caesium carbonate; In tetrahydrofuran; at 160 ℃; for 0.25h; microwave irradiation;

DOI:10.1016/j.tetlet.2008.03.040

upstream raw materials:

3-(N,N-dimethylamino)phenylboronic acid

3-bromo-4,7-dichloro-6-iodoquinoline

Downstream raw materials:

C₂₄H₂₀Cl₂N₂