Technology Process of C18H28O5
There total 8 articles about C18H28O5 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
acetic acid; tetramethylammonium triacetoxyborohydride;
In
acetonitrile;
at -35 ℃;
for 20h;
diastereoselective reaction;
DOI:10.1055/s-0030-1260784
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: diisobutylaluminium hydride / diethyl ether / 1.5 h / -78 °C
2.1: tin(IV) chloride / dichloromethane / 1 h / -78 °C
3.1: 1H-imidazole / N,N-dimethyl-formamide / 2.5 h / 20 °C
4.1: lithium diisopropyl amide / tetrahydrofuran / 1 h / -78 °C
4.2: 2 h / -78 - 0 °C
5.1: tetrabutyl ammonium fluoride / tetrahydrofuran
6.1: acetic acid; tetramethylammonium triacetoxyborohydride / acetonitrile / 20 h / -35 °C
With
1H-imidazole; tetrabutyl ammonium fluoride; tin(IV) chloride; diisobutylaluminium hydride; acetic acid; tetramethylammonium triacetoxyborohydride; lithium diisopropyl amide;
In
tetrahydrofuran; diethyl ether; dichloromethane; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1055/s-0030-1260784
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: trimethylsilyl trifluoromethanesulfonate / dichloromethane / 5 h / 0 - 20 °C
2.1: diisobutylaluminium hydride / diethyl ether / 1.5 h / -78 °C
3.1: tin(IV) chloride / dichloromethane / 1 h / -78 °C
4.1: 1H-imidazole / N,N-dimethyl-formamide / 2.5 h / 20 °C
5.1: lithium diisopropyl amide / tetrahydrofuran / 1 h / -78 °C
5.2: 2 h / -78 - 0 °C
6.1: tetrabutyl ammonium fluoride / tetrahydrofuran
7.1: acetic acid; tetramethylammonium triacetoxyborohydride / acetonitrile / 20 h / -35 °C
With
1H-imidazole; trimethylsilyl trifluoromethanesulfonate; tetrabutyl ammonium fluoride; tin(IV) chloride; diisobutylaluminium hydride; acetic acid; tetramethylammonium triacetoxyborohydride; lithium diisopropyl amide;
In
tetrahydrofuran; diethyl ether; dichloromethane; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1055/s-0030-1260784
