tert-butyl (2S)-2-[4-(2-ethoxy-2-oxoacetyl)phenoxy]methyl-1-pyrrolidinecarboxylate

Base Information

Chemical Name:tert-butyl (2S)-2-[4-(2-ethoxy-2-oxoacetyl)phenoxy]methyl-1-pyrrolidinecarboxylate
CAS No.:150610-41-6
Molecular Formula:C₂₀H₂₇NO₆
Molecular Weight:377.437
Hs Code.:

Synonyms:tert-butyl (2S)-2-[4-(2-ethoxy-2-oxoacetyl)phenoxy]methyl-1-pyrrolidinecarboxylate

Suppliers and Price of tert-butyl (2S)-2-[4-(2-ethoxy-2-oxoacetyl)phenoxy]methyl-1-pyrrolidinecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of tert-butyl (2S)-2-[4-(2-ethoxy-2-oxoacetyl)phenoxy]methyl-1-pyrrolidinecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of tert-butyl (2S)-2-[4-(2-ethoxy-2-oxoacetyl)phenoxy]methyl-1-pyrrolidinecarboxylate

There total 2 articles about tert-butyl (2S)-2-[4-(2-ethoxy-2-oxoacetyl)phenoxy]methyl-1-pyrrolidinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

: 70080-54-5
4-hydroxy-alpha-oxobenzeneacetic acid ethyl ester

: 69610-40-8
N-(tert-butoxycarbonyl)-L-prolinol

: 150610-41-6
tert-butyl (2S)-2-[4-(2-ethoxy-2-oxoacetyl)phenoxy]methyl-1-pyrrolidinecarboxylate

Guidance literature:: With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; at 20 ℃; for 24h;
DOI:10.1016/j.bmc.2004.02.032

Reference yield:

: 150610-41-6
tert-butyl (2S)-2-[4-(2-ethoxy-2-oxoacetyl)phenoxy]methyl-1-pyrrolidinecarboxylate

Guidance literature:

Reference yield:

: 150610-41-6
tert-butyl (2S)-2-[4-(2-ethoxy-2-oxoacetyl)phenoxy]methyl-1-pyrrolidinecarboxylate

: 701305-46-6
ethyl 2-(4-{[(2S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl]methoxy}phenyl)-3-(7-cyano-2-naphthyl)propanoate

Guidance literature:: Multi-step reaction with 2 steps

1: 1,8-diazabicyclo[5.4.0]undec-7-ene / ethanol; tetrahydrofuran / 3 h / 20 °C

2: H₂ / PdO*H₂O/BaSO₄ / tetrahydrofuran / 20 °C / 760 Torr

With hydrogen; 1,8-diazabicyclo[5.4.0]undec-7-ene; palladium(II) oxide; barium sulfate; In tetrahydrofuran; ethanol; 1: Wittig reaction;
DOI:10.1016/j.bmc.2004.02.032