[[N-[1-(2,6-dichlorophenyl)methyl]-3-(1-pyrrolidinylmethyl)-1H-indol-5-yl]aminocarbonyl]-glycine-N-γ-t-butoxycarbonyl-L-α,γ-diaminobutyrate-L-phenylalanine-N-benzylamide

Base Information

Chemical Name:[[N-[1-(2,6-dichlorophenyl)methyl]-3-(1-pyrrolidinylmethyl)-1H-indol-5-yl]aminocarbonyl]-glycine-N-γ-t-butoxycarbonyl-L-α,γ-diaminobutyrate-L-phenylalanine-N-benzylamide
CAS No.:880546-24-7
Molecular Formula:C₄₈H₅₆Cl₂N₈O₆
Molecular Weight:911.929
Hs Code.:

[[N-[1-(2,6-dichlorophenyl)methyl]-3-(1-pyrrolidinylmethyl)-1H-indol-5-yl]aminocarbonyl]-glycine-N-γ-t-butoxycarbonyl-L-α,γ-diaminobutyrate-L-phenylalanine-N-benzylamide

Synonyms:[[N-[1-(2,6-dichlorophenyl)methyl]-3-(1-pyrrolidinylmethyl)-1H-indol-5-yl]aminocarbonyl]-glycine-N-γ-t-butoxycarbonyl-L-α,γ-diaminobutyrate-L-phenylalanine-N-benzylamide

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Chemical Property of [[N-[1-(2,6-dichlorophenyl)methyl]-3-(1-pyrrolidinylmethyl)-1H-indol-5-yl]aminocarbonyl]-glycine-N-γ-t-butoxycarbonyl-L-α,γ-diaminobutyrate-L-phenylalanine-N-benzylamide

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Technology Process of [[N-[1-(2,6-dichlorophenyl)methyl]-3-(1-pyrrolidinylmethyl)-1H-indol-5-yl]aminocarbonyl]-glycine-N-γ-t-butoxycarbonyl-L-α,γ-diaminobutyrate-L-phenylalanine-N-benzylamide

There total 1 articles about [[N-[1-(2,6-dichlorophenyl)methyl]-3-(1-pyrrolidinylmethyl)-1H-indol-5-yl]aminocarbonyl]-glycine-N-γ-t-butoxycarbonyl-L-α,γ-diaminobutyrate-L-phenylalanine-N-benzylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 880546-15-6
5-phenyloxycarbonylamino-3-(1-pyrrolidinylmethyl)-N-[1-(2,6-dichlorophenyl) methyl]-1H-indole

: 880546-23-6
glycine-N-γ-t-butoxycarbonyl-L-α,γ-diaminobutyrate-L-phenylalanine-N-benzylamide

: 880546-24-7
[[N-[1-(2,6-dichlorophenyl)methyl]-3-(1-pyrrolidinylmethyl)-1H-indol-5-yl]aminocarbonyl]-glycine-N-γ-t-butoxycarbonyl-L-α,γ-diaminobutyrate-L-phenylalanine-N-benzylamide

Guidance literature:: With triethylamine; In 1,2-dichloro-ethane; at 80 ℃; for 3h;

Reference yield: 64.0%

: 880546-24-7
[[N-[1-(2,6-dichlorophenyl)methyl]-3-(1-pyrrolidinylmethyl)-1H-indol-5-yl]aminocarbonyl]-glycine-N-γ-t-butoxycarbonyl-L-α,γ-diaminobutyrate-L-phenylalanine-N-benzylamide

: K-12940

Guidance literature:: [[N-[1-(2,6-dichlorophenyl)methyl]-3-(1-pyrrolidinylmethyl)-1H-indol-5-yl]aminocarbonyl]-glycine-N-γ-t-butoxycarbonyl-L-α,γ-diaminobutyrate-L-phenylalanine-N-benzylamide; With trifluoroacetic acid; In dichloromethane; at 0 ℃; for 0.5h;

With sodium hydroxide; In dichloromethane; water; at 0 ℃; pH=12;