4-chloro-benzoic acid-(2,4-diamino-6-oxo-1,6-dihydro-pyrimidin-5-ylamide)

Base Information

• Chemical Name: 4-chloro-benzoic acid-(2,4-diamino-6-oxo-1,6-dihydro-pyrimidin-5-ylamide)
• CAS No.: 412312-49-3
• Molecular Formula: C₁₁H₁₀ClN₅O₂
• Molecular Weight: 279.686

Synonyms:4-chloro-benzoic acid-(2,4-diamino-6-oxo-1,6-dihydro-pyrimidin-5-ylamide)

Chemical Property of 4-chloro-benzoic acid-(2,4-diamino-6-oxo-1,6-dihydro-pyrimidin-5-ylamide)

Chemical Property:

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Technology Process of 4-chloro-benzoic acid-(2,4-diamino-6-oxo-1,6-dihydro-pyrimidin-5-ylamide)

There total 1 articles about 4-chloro-benzoic acid-(2,4-diamino-6-oxo-1,6-dihydro-pyrimidin-5-ylamide) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 4-chloro-benzoic acid-(2,4-diamino-6-oxo-1,6-dihydro-pyrimidin-5-ylamide) (412312-49-3)

Guidance literature:

/BRN= 251122/;

DOI:10.1021/ja01155a070

Reference yield:

4-chloro-benzoic acid-(2,4-diamino-6-oxo-1,6-dihydro-pyrimidin-5-ylamide) (412312-49-3) → 2-(4-chloro-phenyl)-thiazolo[5,4-d]pyrimidine-5,7-diyldiamine

Guidance literature:

With tetraphosphorus decasulfide; tetralin; at 180 ℃;

DOI:10.1021/ja01163a112

Reference yield:

4-chloro-benzoic acid-(2,4-diamino-6-oxo-1,6-dihydro-pyrimidin-5-ylamide) (412312-49-3) → 2-(4-chloro-phenyl)-oxazolo[5,4-d]pyrimidine-5,7-diyldiamine (18620-98-9) + 6-chloro-8-(4-chloro-phenyl)-7(9)H-purin-2-ylamine (688364-68-3)

Guidance literature:

With trichlorophosphate;

DOI:10.1021/ja01139a049

Downstream raw materials:

2-(4-chloro-phenyl)-oxazolo[5,4-d]pyrimidine-5,7-diyldiamine

6-chloro-8-(4-chloro-phenyl)-7⁽⁹⁾H-purin-2-ylamine

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