1-(Thiophen-3-yl)propan-2-amine hydrochloride

Base Information

Chemical Name:1-(Thiophen-3-yl)propan-2-amine hydrochloride
CAS No.:86188-25-2
Molecular Formula:C₇H₁₁NS*ClH
Molecular Weight:177.698
Hs Code.:

Synonyms:86188-25-2;1-(Thiophen-3-yl)propan-2-amine hydrochloride;[1-Methyl-2-(3-thienyl)ethyl]amine hydrochloride;1-thiophen-3-ylpropan-2-amine;hydrochloride;1-(THIOPHEN-3-YL)PROPAN-2-AMINE HCL;SCHEMBL9433817;MFCD13186055;AKOS027426937;AS-43269;1-(Thiophen-3-yl)propan-2-aminehydrochloride

Suppliers and Price of 1-(Thiophen-3-yl)propan-2-amine hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 1-(Thiophen-3-yl)propan-2-amine hydrochloride

Chemical Property:

Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:177.0378983
Heavy Atom Count:10
Complexity:85

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(CC1=CSC=C1)N.Cl

Technology Process of 1-(Thiophen-3-yl)propan-2-amine hydrochloride

There total 4 articles about 1-(Thiophen-3-yl)propan-2-amine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.01%

: 3-(2-nitroprop-1-enyl)thiophene

: 86188-25-2
(RS)-1-(thiophen-3-yl)propan-2-amine hydrochloride

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; Inert atmosphere; Cooling with ice; Reflux;
DOI:10.3390/molecules24020259

Reference yield: 71.4%

: 149977-36-6
(E)-3-(2-nitroprop-1-en-1-yl)thiophene

: 86188-25-2
(RS)-1-(thiophen-3-yl)propan-2-amine hydrochloride

Guidance literature:: (E)-3-(2-nitroprop-1-en-1-yl)thiophene; With lithium aluminium tetrahydride; In tetrahydrofuran; for 3h; Cooling with ice; Inert atmosphere; Reflux;

With hydrogenchloride; In diethyl ether;

Reference yield:

: 498-62-4
3-thiophene carboxaldehyde

: 86188-25-2
(RS)-1-(thiophen-3-yl)propan-2-amine hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1.1: formic acid; ethanolamine / 7 h / 85 - 90 °C / Cooling with ice

2.1: lithium aluminium tetrahydride / tetrahydrofuran / 0.5 h / Reflux

2.2: 0 °C

With lithium aluminium tetrahydride; formic acid; ethanolamine; In tetrahydrofuran;