3-(2-acetamidoethyl)-6-(2-dibenzylaminoethyl)-2(3H)-benzoxazolinone

Base Information

• Chemical Name: 3-(2-acetamidoethyl)-6-(2-dibenzylaminoethyl)-2(3H)-benzoxazolinone
• CAS No.: 340166-97-4
• Molecular Formula: C₂₇H₂₉N₃O₃
• Molecular Weight: 443.546
• Mol file: 340166-97-4.mol

Synonyms:3-(2-acetamidoethyl)-6-(2-dibenzylaminoethyl)-2(3H)-benzoxazolinone

Chemical Property of 3-(2-acetamidoethyl)-6-(2-dibenzylaminoethyl)-2(3H)-benzoxazolinone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(2-acetamidoethyl)-6-(2-dibenzylaminoethyl)-2(3H)-benzoxazolinone

There total 4 articles about 3-(2-acetamidoethyl)-6-(2-dibenzylaminoethyl)-2(3H)-benzoxazolinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

acetic anhydride (108-24-7) + 3-cyanomethyl-6-(2-dibenzylaminoethyl)-2(3H)-benzoxazolinone (340166-96-3) → 3-(2-acetamidoethyl)-6-(2-dibenzylaminoethyl)-2(3H)-benzoxazolinone (340166-97-4)

Guidance literature:

With hydrogen; nickel; at 60 ℃; for 6h; under 45003.6 Torr;

DOI:10.1080/00304940109356576

Reference yield:

6-(2-bromoethyl-)benzoxazolone (92584-74-2) → 3-(2-acetamidoethyl)-6-(2-dibenzylaminoethyl)-2(3H)-benzoxazolinone (340166-97-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 78 percent / acetonitrile / 72 h / Heating

2: 83 percent / EtONa / ethanol; dimethylformamide / 10 h / 80 °C

3: 71 percent / hydrogen / Raney nickel / 6 h / 60 °C / 45003.6 Torr

With hydrogen; sodium ethanolate; nickel; In ethanol; N,N-dimethyl-formamide; acetonitrile;

DOI:10.1080/00304940109356576

Reference yield:

6-(2-dibenzylaminoethyl)-2(3H)-benzoxazolinone (92584-65-1) → 3-(2-acetamidoethyl)-6-(2-dibenzylaminoethyl)-2(3H)-benzoxazolinone (340166-97-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 83 percent / EtONa / ethanol; dimethylformamide / 10 h / 80 °C

2: 71 percent / hydrogen / Raney nickel / 6 h / 60 °C / 45003.6 Torr

With hydrogen; sodium ethanolate; nickel; In ethanol; N,N-dimethyl-formamide;

DOI:10.1080/00304940109356576

upstream raw materials:

acetic anhydride

3-cyanomethyl-6-(2-dibenzylaminoethyl)-2(3H)-benzoxazolinone

6-(2-bromoethyl-)benzoxazolone

6-(2-dibenzylaminoethyl)-2(3H)-benzoxazolinone