4'-[((1R,5S,7R)-3-Methyl-2,4-dioxo-1,5,7-tripropyl-3-aza-bicyclo[3.3.1]nonane-7-carbonyl)-amino]-biphenyl-4-carboxylic acid pentafluorophenyl ester

Base Information

Chemical Name:4'-[((1R,5S,7R)-3-Methyl-2,4-dioxo-1,5,7-tripropyl-3-aza-bicyclo[3.3.1]nonane-7-carbonyl)-amino]-biphenyl-4-carboxylic acid pentafluorophenyl ester
CAS No.:137058-72-1
Molecular Formula:C₃₈H₃₉F₅N₂O₅
Molecular Weight:698.73
Hs Code.:

Synonyms:4'-[((1R,5S,7R)-3-Methyl-2,4-dioxo-1,5,7-tripropyl-3-aza-bicyclo[3.3.1]nonane-7-carbonyl)-amino]-biphenyl-4-carboxylic acid pentafluorophenyl ester

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Chemical Property of 4'-[((1R,5S,7R)-3-Methyl-2,4-dioxo-1,5,7-tripropyl-3-aza-bicyclo[3.3.1]nonane-7-carbonyl)-amino]-biphenyl-4-carboxylic acid pentafluorophenyl ester

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Technology Process of 4'-[((1R,5S,7R)-3-Methyl-2,4-dioxo-1,5,7-tripropyl-3-aza-bicyclo[3.3.1]nonane-7-carbonyl)-amino]-biphenyl-4-carboxylic acid pentafluorophenyl ester

There total 6 articles about 4'-[((1R,5S,7R)-3-Methyl-2,4-dioxo-1,5,7-tripropyl-3-aza-bicyclo[3.3.1]nonane-7-carbonyl)-amino]-biphenyl-4-carboxylic acid pentafluorophenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 41567-99-1
4-(4'-nitrophenyl)benzoyl chloride

: 137058-72-1
4'-[((1R,5S,7R)-3-Methyl-2,4-dioxo-1,5,7-tripropyl-3-aza-bicyclo[3.3.1]nonane-7-carbonyl)-amino]-biphenyl-4-carboxylic acid pentafluorophenyl ester

Guidance literature:: Multi-step reaction with 5 steps

2: Fe/HCl

3: pyridine, DMAP

4: H₂ / Pd

5: DCC

With pyridine; hydrogenchloride; dmap; hydrogen; iron; dicyclohexyl-carbodiimide; palladium;
DOI:10.1021/ja00024a089

Reference yield:

: 137058-70-9
4'-amino-1,1'-biphenyl-4-carboxylic acid benzyl ester

: 137058-72-1
4'-[((1R,5S,7R)-3-Methyl-2,4-dioxo-1,5,7-tripropyl-3-aza-bicyclo[3.3.1]nonane-7-carbonyl)-amino]-biphenyl-4-carboxylic acid pentafluorophenyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine, DMAP

2: H₂ / Pd

3: DCC

With pyridine; dmap; hydrogen; dicyclohexyl-carbodiimide; palladium;
DOI:10.1021/ja00024a089

Reference yield:

: 137058-75-4
(1R,5S,7S)-3-Methyl-2,4-dioxo-1,5,7-tripropyl-3-aza-bicyclo[3.3.1]nonane-7-carbonyl chloride

: 137058-72-1
4'-[((1R,5S,7R)-3-Methyl-2,4-dioxo-1,5,7-tripropyl-3-aza-bicyclo[3.3.1]nonane-7-carbonyl)-amino]-biphenyl-4-carboxylic acid pentafluorophenyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine, DMAP

2: H₂ / Pd

3: DCC

With pyridine; dmap; hydrogen; dicyclohexyl-carbodiimide; palladium;
DOI:10.1021/ja00024a089