Technology Process of 3,5,7-tri-O-benzyl-6-desoxy-1,2-O-isopropylidene-6-nitro-D,L-glycero-α-D-glucoheptafuranose
There total 1 articles about 3,5,7-tri-O-benzyl-6-desoxy-1,2-O-isopropylidene-6-nitro-D,L-glycero-α-D-glucoheptafuranose which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 75 percent / tetrabutylammonium fluoride / tetrahydrofuran / 10 h / 20 °C
2: 46 percent / trifluoromethanesulphonic acid / cyclohexane; CH2Cl2 / 16 h / 20 °C
With
trifluorormethanesulfonic acid; tetrabutyl ammonium fluoride;
In
tetrahydrofuran; dichloromethane; cyclohexane;
1: Henry reaction;
DOI:10.1021/ol035771x
- Guidance literature:
-
With
water; trifluoroacetic acid;
In
1,4-dioxane;
at 20 ℃;
for 48h;
DOI:10.1021/ol035771x
- Guidance literature:
-
Multi-step reaction with 4 steps
1: trifluoroacetic acid; H2O / dioxane / 48 h / 20 °C
2: 0.042 g / aq. sodium bicarbonate / methanol / 14 h / 20 °C
3: 81 percent / p-toluenesulphonic acid / 72 h / 20 °C
4: 70 percent / pyridinium p-toluenesulfonate / CH2Cl2 / 2.5 h / Heating
With
water; pyridinium p-toluenesulfonate; sodium hydrogencarbonate; toluene-4-sulfonic acid; trifluoroacetic acid;
In
1,4-dioxane; methanol; dichloromethane;
2: Henry reaction;
DOI:10.1021/ol035771x
