3-[3-(2-methoxyphenylsulfonyloxy)-5-methylphenoxy]propoxyamine

Base Information

• Chemical Name: 3-[3-(2-methoxyphenylsulfonyloxy)-5-methylphenoxy]propoxyamine
• CAS No.: 208642-79-9
• Molecular Formula: C₁₇H₂₁NO₆S
• Molecular Weight: 367.423
• Mol file: 208642-79-9.mol

Synonyms:3-[3-(2-methoxyphenylsulfonyloxy)-5-methylphenoxy]propoxyamine

Chemical Property of 3-[3-(2-methoxyphenylsulfonyloxy)-5-methylphenoxy]propoxyamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-[3-(2-methoxyphenylsulfonyloxy)-5-methylphenoxy]propoxyamine

There total 3 articles about 3-[3-(2-methoxyphenylsulfonyloxy)-5-methylphenoxy]propoxyamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

N-[3-[3-(2-methoxyphenylsulfonyloxy)-5-methylphenoxy]propoxy]phthalimide (208642-78-8) → 3-[3-(2-methoxyphenylsulfonyloxy)-5-methylphenoxy]propoxyamine (208642-79-9)

Guidance literature:

With hydrogenchloride; sodium borohydrid; In water; isopropyl alcohol;

Reference yield:

3-(2-methoxyphenylsulfonyloxy)-5-methylphenol (197959-77-6) → 3-[3-(2-methoxyphenylsulfonyloxy)-5-methylphenoxy]propoxyamine (208642-79-9)

Guidance literature:

Multi-step reaction with 3 steps

1: TBP; ADDP / tetrahydrofuran

2: TPP; DEAD / tetrahydrofuran

3: 40 percent aq. NH₂CH₃ / ethanol

With bithionol; thiamine diphosphate; methylamine; 1,1'-azodicarbonyl-dipiperidine; diethylazodicarboxylate; In tetrahydrofuran; ethanol; 1: Mitsunobu reaction / 2: Mitsunobu reaction;

DOI:10.1016/S0960-894X(03)00125-2

Reference yield:

3-[3-(2-methoxyphenylsulfonyloxy)-5-methylphenoxy]propanol (197959-78-7) → 3-[3-(2-methoxyphenylsulfonyloxy)-5-methylphenoxy]propoxyamine (208642-79-9)

Guidance literature:

Multi-step reaction with 2 steps

1: TPP; DEAD / tetrahydrofuran

2: 40 percent aq. NH₂CH₃ / ethanol

With thiamine diphosphate; methylamine; diethylazodicarboxylate; In tetrahydrofuran; ethanol; 1: Mitsunobu reaction;

DOI:10.1016/S0960-894X(03)00125-2

upstream raw materials:

N-[3-[3-(2-methoxyphenylsulfonyloxy)-5-methylphenoxy]propoxy]phthalimide

3-(2-methoxyphenylsulfonyloxy)-5-methylphenol

3-[3-(2-methoxyphenylsulfonyloxy)-5-methylphenoxy]propanol