3-(4-(1,2,5,6-tetrahydropyrid-4-yl)-3,5-difluorophenyl)-5(R)-acetoxymethyloxazolidin-2-one hydrochloride

Base Information

Chemical Name:3-(4-(1,2,5,6-tetrahydropyrid-4-yl)-3,5-difluorophenyl)-5(R)-acetoxymethyloxazolidin-2-one hydrochloride
CAS No.:264600-69-3
Molecular Formula:C₁₇H₁₈F₂N₂O₄*ClH
Molecular Weight:388.799
Hs Code.:

Synonyms:3-(4-(1,2,5,6-tetrahydropyrid-4-yl)-3,5-difluorophenyl)-5(R)-acetoxymethyloxazolidin-2-one hydrochloride

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Chemical Property of 3-(4-(1,2,5,6-tetrahydropyrid-4-yl)-3,5-difluorophenyl)-5(R)-acetoxymethyloxazolidin-2-one hydrochloride

Chemical Property:

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Technology Process of 3-(4-(1,2,5,6-tetrahydropyrid-4-yl)-3,5-difluorophenyl)-5(R)-acetoxymethyloxazolidin-2-one hydrochloride

There total 3 articles about 3-(4-(1,2,5,6-tetrahydropyrid-4-yl)-3,5-difluorophenyl)-5(R)-acetoxymethyloxazolidin-2-one hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₈H₁₉ClF₂N₂O₄

: 264600-69-3
3-(4-(1,2,5,6-tetrahydropyrid-4-yl)-3,5-difluorophenyl)-5(R)-acetoxymethyloxazolidin-2-one hydrochloride

Guidance literature:: With methanol; for 18h;

Reference yield:

: 264600-68-2
3-(4-(1-benzyl-1,2,5,6-tetrahydropyrid-4-yl)-3,5-difluorophenyl)-5(R)-acetoxymethyloxazolidin-2-one

: 264600-69-3
3-(4-(1,2,5,6-tetrahydropyrid-4-yl)-3,5-difluorophenyl)-5(R)-acetoxymethyloxazolidin-2-one hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: dichloromethane / 1 h / 0 °C

2: methanol / 18 h

With methanol; In dichloromethane;

Reference yield:

: 252328-82-8
MMV₆₈₇₇₂₉

: 264600-69-3
3-(4-(1,2,5,6-tetrahydropyrid-4-yl)-3,5-difluorophenyl)-5(R)-acetoxymethyloxazolidin-2-one hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: dmap; triethylamine / dichloromethane / 1 h / 0 - 20 °C

2: dichloromethane / 1 h / 0 °C

3: methanol / 18 h

With methanol; dmap; triethylamine; In dichloromethane;