N-benzyl-N-{(E)-(3S)-[2-((3aR,8aS)-2,2-dimethyl-8,8a-dihydro-3aH-indeno[1,2-d]oxazol-3-yl)-2-oxoethoxy]-5-(4-methoxybenzyloxy)pent-1-enyl}-4-methylbenzenesulfonamide

Base Information

Chemical Name:N-benzyl-N-{(E)-(3S)-[2-((3aR,8aS)-2,2-dimethyl-8,8a-dihydro-3aH-indeno[1,2-d]oxazol-3-yl)-2-oxoethoxy]-5-(4-methoxybenzyloxy)pent-1-enyl}-4-methylbenzenesulfonamide
CAS No.:1300117-39-8
Molecular Formula:C₄₁H₄₆N₂O₇S
Molecular Weight:710.891
Hs Code.:

N-benzyl-N-{(E)-(3S)-[2-((3aR,8aS)-2,2-dimethyl-8,8a-dihydro-3aH-indeno[1,2-d]oxazol-3-yl)-2-oxoethoxy]-5-(4-methoxybenzyloxy)pent-1-enyl}-4-methylbenzenesulfonamide

Synonyms:N-benzyl-N-{(E)-(3S)-[2-((3aR,8aS)-2,2-dimethyl-8,8a-dihydro-3aH-indeno[1,2-d]oxazol-3-yl)-2-oxoethoxy]-5-(4-methoxybenzyloxy)pent-1-enyl}-4-methylbenzenesulfonamide

Suppliers and Price of N-benzyl-N-{(E)-(3S)-[2-((3aR,8aS)-2,2-dimethyl-8,8a-dihydro-3aH-indeno[1,2-d]oxazol-3-yl)-2-oxoethoxy]-5-(4-methoxybenzyloxy)pent-1-enyl}-4-methylbenzenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-benzyl-N-{(E)-(3S)-[2-((3aR,8aS)-2,2-dimethyl-8,8a-dihydro-3aH-indeno[1,2-d]oxazol-3-yl)-2-oxoethoxy]-5-(4-methoxybenzyloxy)pent-1-enyl}-4-methylbenzenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-benzyl-N-{(E)-(3S)-[2-((3aR,8aS)-2,2-dimethyl-8,8a-dihydro-3aH-indeno[1,2-d]oxazol-3-yl)-2-oxoethoxy]-5-(4-methoxybenzyloxy)pent-1-enyl}-4-methylbenzenesulfonamide

There total 9 articles about N-benzyl-N-{(E)-(3S)-[2-((3aR,8aS)-2,2-dimethyl-8,8a-dihydro-3aH-indeno[1,2-d]oxazol-3-yl)-2-oxoethoxy]-5-(4-methoxybenzyloxy)pent-1-enyl}-4-methylbenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 776315-69-6
2-bromo-1-(2,2-dimethyl-8,8a-dihydro-3aH-indeno[1,2-d]oxazol-3-yl)-ethanone

: 1300116-98-6
N-benzyl-N-[(E)-(3S)-3-hydroxy-5-(4-methoxybenzyloxy)pent-1-enyl]-4-methylbenzenesulfonamide

: 108-24-7
acetic anhydride

: C₂₉H₃₃NO₆S

: 1300117-39-8
N-benzyl-N-{(E)-(3S)-[2-((3aR,8aS)-2,2-dimethyl-8,8a-dihydro-3aH-indeno[1,2-d]oxazol-3-yl)-2-oxoethoxy]-5-(4-methoxybenzyloxy)pent-1-enyl}-4-methylbenzenesulfonamide

Guidance literature:: 2-bromo-1-(2,2-dimethyl-8,8a-dihydro-3aH-indeno[1,2-d]oxazol-3-yl)-ethanone; N-benzyl-N-[(E)-(3S)-3-hydroxy-5-(4-methoxybenzyloxy)pent-1-enyl]-4-methylbenzenesulfonamide; With tetra(n-butyl)ammonium hydrogensulfate; sodium hydroxide; In water; toluene; at 20 ℃; for 3h;

acetic anhydride; With dmap; triethylamine; In dichloromethane; at 20 ℃; for 2.5h;
DOI:10.1002/chem.201003265

Reference yield:

: 1195470-99-5
5-(4-methoxybenzyloxy)-1-trimethylsilylpent-1-yne-3-ol

: 1300117-39-8
N-benzyl-N-{(E)-(3S)-[2-((3aR,8aS)-2,2-dimethyl-8,8a-dihydro-3aH-indeno[1,2-d]oxazol-3-yl)-2-oxoethoxy]-5-(4-methoxybenzyloxy)pent-1-enyl}-4-methylbenzenesulfonamide

Guidance literature:: Multi-step reaction with 8 steps

1.1: sodium acetate; pyridinium chlorochromate / dichloromethane; water / 2 h / 20 °C / Molecular sieve

2.1: Noyori's catalyst / isopropyl alcohol / 2.5 h / 20 °C

3.1: 1H-imidazole / N,N-dimethyl-formamide / 4 h / 20 °C

4.1: N-Bromosuccinimide; silver nitrate / acetone / 17 h / 20 °C / Darkness

5.1: potassium phosphate; copper(ll) sulfate pentahydrate; 1,10-Phenanthroline / toluene / 12 h / 80 °C

6.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 20 °C

7.1: sodium bis(2-methoxyethoxy)aluminium dihydride / tetrahydrofuran; toluene / 0.25 h / 20 °C

8.1: tetra(n-butyl)ammonium hydrogensulfate; sodium hydroxide / water; toluene / 3 h / 20 °C

8.2: 2.5 h / 20 °C

With 1H-imidazole; potassium phosphate; N-Bromosuccinimide; Noyori's catalyst; 1,10-Phenanthroline; copper(ll) sulfate pentahydrate; tetrabutyl ammonium fluoride; sodium acetate; tetra(n-butyl)ammonium hydrogensulfate; silver nitrate; sodium bis(2-methoxyethoxy)aluminium dihydride; pyridinium chlorochromate; sodium hydroxide; In tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide; isopropyl alcohol; acetone; toluene;
DOI:10.1002/chem.201003265

Reference yield:

: 1195470-78-0
1-trimethylsilyl-5-(4-methoxybenzyloxy)-1-pentyn-3-one

: 1300117-39-8
N-benzyl-N-{(E)-(3S)-[2-((3aR,8aS)-2,2-dimethyl-8,8a-dihydro-3aH-indeno[1,2-d]oxazol-3-yl)-2-oxoethoxy]-5-(4-methoxybenzyloxy)pent-1-enyl}-4-methylbenzenesulfonamide

Guidance literature:: Multi-step reaction with 7 steps

1.1: Noyori's catalyst / isopropyl alcohol / 2.5 h / 20 °C

2.1: 1H-imidazole / N,N-dimethyl-formamide / 4 h / 20 °C

3.1: N-Bromosuccinimide; silver nitrate / acetone / 17 h / 20 °C / Darkness

4.1: potassium phosphate; copper(ll) sulfate pentahydrate; 1,10-Phenanthroline / toluene / 12 h / 80 °C

5.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 20 °C

6.1: sodium bis(2-methoxyethoxy)aluminium dihydride / tetrahydrofuran; toluene / 0.25 h / 20 °C

7.1: tetra(n-butyl)ammonium hydrogensulfate; sodium hydroxide / water; toluene / 3 h / 20 °C

7.2: 2.5 h / 20 °C

With 1H-imidazole; potassium phosphate; N-Bromosuccinimide; Noyori's catalyst; 1,10-Phenanthroline; copper(ll) sulfate pentahydrate; tetrabutyl ammonium fluoride; tetra(n-butyl)ammonium hydrogensulfate; silver nitrate; sodium bis(2-methoxyethoxy)aluminium dihydride; sodium hydroxide; In tetrahydrofuran; water; N,N-dimethyl-formamide; isopropyl alcohol; acetone; toluene;
DOI:10.1002/chem.201003265