Ethanone, 2-chloro-1-(2,2-dimethyl-1,3-dioxolan-4-yl)-, (R)- (9CI)

Base Information

Chemical Name:Ethanone, 2-chloro-1-(2,2-dimethyl-1,3-dioxolan-4-yl)-, (R)- (9CI)
CAS No.:85364-10-9
Molecular Formula:C₇H₁₁ClO₃
Molecular Weight:178.616
Hs Code.:
Mol file:85364-10-9.mol

Synonyms:Ethanone, 2-chloro-1-(2,2-dimethyl-1,3-dioxolan-4-yl)-, (R)- (9CI)

Suppliers and Price of Ethanone, 2-chloro-1-(2,2-dimethyl-1,3-dioxolan-4-yl)-, (R)- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Ethanone, 2-chloro-1-(2,2-dimethyl-1,3-dioxolan-4-yl)-, (R)- (9CI)

Chemical Property:

PSA：35.53000
LogP:0.94580

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Ethanone, 2-chloro-1-(2,2-dimethyl-1,3-dioxolan-4-yl)-, (R)- (9CI)

There total 4 articles about Ethanone, 2-chloro-1-(2,2-dimethyl-1,3-dioxolan-4-yl)-, (R)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 85364-09-6
(R)-4-((Z)-2-Chloro-1-methoxy-vinyl)-2,2-dimethyl-[1,3]dioxolane

: 85364-10-9,90493-97-3
2-chloro-1-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]ethanone

Guidance literature:: With toluene-4-sulfonic acid; In acetone; for 24h; Ambient temperature;
DOI:10.1016/S0040-4039(00)85717-2

Reference yield: 30.0%

: 593-71-5
Chloroiodomethane

: 52373-72-5
methyl (R)-2,2-dimethyl-1,3-dioxolane-4-carboxylate

: 85364-10-9,90493-97-3
2-chloro-1-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]ethanone

Guidance literature:: With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃; for 0.333333h; Inert atmosphere;

Reference yield:

: 85364-08-5
(R)-4-(2,2-Dichloro-1-methoxy-ethyl)-2,2-dimethyl-[1,3]dioxolane

: 85364-10-9,90493-97-3
2-chloro-1-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]ethanone

Guidance literature:: Multi-step reaction with 2 steps

1: 84 percent / KOH / ethanol / 2 h / Heating

2: 95 percent / TsOH / acetone / 24 h / Ambient temperature

With potassium hydroxide; toluene-4-sulfonic acid; In ethanol; acetone;
DOI:10.1016/S0040-4039(00)85717-2