methyl (E)-3-[2-n-butyl-1-{(2-chlorophenyl)methyl}-1H-imidazol-5-yl]-2-(thien-3-yl)methyl-2-butenoate

Base Information

Chemical Name:methyl (E)-3-[2-n-butyl-1-{(2-chlorophenyl)methyl}-1H-imidazol-5-yl]-2-(thien-3-yl)methyl-2-butenoate
CAS No.:135123-72-7
Molecular Formula:C₂₄H₂₇ClN₂O₂S
Molecular Weight:443.01
Hs Code.:

Synonyms:methyl (E)-3-[2-n-butyl-1-{(2-chlorophenyl)methyl}-1H-imidazol-5-yl]-2-(thien-3-yl)methyl-2-butenoate

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Chemical Property of methyl (E)-3-[2-n-butyl-1-{(2-chlorophenyl)methyl}-1H-imidazol-5-yl]-2-(thien-3-yl)methyl-2-butenoate

Chemical Property:

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Technology Process of methyl (E)-3-[2-n-butyl-1-{(2-chlorophenyl)methyl}-1H-imidazol-5-yl]-2-(thien-3-yl)methyl-2-butenoate

There total 4 articles about methyl (E)-3-[2-n-butyl-1-{(2-chlorophenyl)methyl}-1H-imidazol-5-yl]-2-(thien-3-yl)methyl-2-butenoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 133486-46-1
trimethyl 3-(3-thienyl)-2-phosphonopropionate

: 133485-76-4
2-butyl-1-<(2-chlorophenyl)methyl>5-acetylimidazole

: 135123-72-7
methyl (E)-3-[2-n-butyl-1-{(2-chlorophenyl)methyl}-1H-imidazol-5-yl]-2-(thien-3-yl)methyl-2-butenoate

Guidance literature:: With sodium; In ethanol;

Reference yield:

: 2-n-butyl-1-(2-chlorophenyl)methyl-1H-imidazol-carboxaldehyde

: 135123-72-7
methyl (E)-3-[2-n-butyl-1-{(2-chlorophenyl)methyl}-1H-imidazol-5-yl]-2-(thien-3-yl)methyl-2-butenoate

Guidance literature:: Multi-step reaction with 3 steps

1: methyllithium / tetrahydrofuran; diethyl ether

2: manganese dioxide / toluene

3: sodium / ethanol

With manganese dioxide; methyllithium; sodium; In tetrahydrofuran; diethyl ether; ethanol; toluene;

Reference yield:

: 133485-75-3
2-n-butyl-1-(2-chlorophenyl)methyl-5-(α-hydroxy)ethyl-1H-imidazole

: 135123-72-7
methyl (E)-3-[2-n-butyl-1-{(2-chlorophenyl)methyl}-1H-imidazol-5-yl]-2-(thien-3-yl)methyl-2-butenoate

Guidance literature:: Multi-step reaction with 2 steps

1: manganese dioxide / toluene

2: sodium / ethanol

With manganese dioxide; sodium; In ethanol; toluene;