tert-butyl(((Z)-4-(5-((E)-hex-3-en-1-yl)furan-2-yl)but-2-en-1-yl)oxy)diphenylsilane

Base Information

• Chemical Name: tert-butyl(((Z)-4-(5-((E)-hex-3-en-1-yl)furan-2-yl)but-2-en-1-yl)oxy)diphenylsilane
• CAS No.: 1610935-36-8
• Molecular Formula: C₃₀H₃₈O₂Si
• Molecular Weight: 458.716
• Mol file: 1610935-36-8.mol

Synonyms:tert-butyl(((Z)-4-(5-((E)-hex-3-en-1-yl)furan-2-yl)but-2-en-1-yl)oxy)diphenylsilane

Chemical Property of tert-butyl(((Z)-4-(5-((E)-hex-3-en-1-yl)furan-2-yl)but-2-en-1-yl)oxy)diphenylsilane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl(((Z)-4-(5-((E)-hex-3-en-1-yl)furan-2-yl)but-2-en-1-yl)oxy)diphenylsilane

There total 5 articles about tert-butyl(((Z)-4-(5-((E)-hex-3-en-1-yl)furan-2-yl)but-2-en-1-yl)oxy)diphenylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

(E)-2-(hex-3-en-1-yl)furan (1610935-34-6) + (Z)-((4-bromobut-2-en-1-yl)oxy)(tert-butyl)diphenylsilane (226546-07-2) → tert-butyl(((Z)-4-(5-((E)-hex-3-en-1-yl)furan-2-yl)but-2-en-1-yl)oxy)diphenylsilane (1610935-36-8)

Guidance literature:

(E)-2-(hex-3-en-1-yl)furan; With n-butyllithium; In tetrahydrofuran; hexane; at 0 ℃; for 0.333333h; Inert atmosphere;

(Z)-((4-bromobut-2-en-1-yl)oxy)(tert-butyl)diphenylsilane; In tetrahydrofuran; hexane; at 0 - 20 ℃; for 4h;

DOI:10.1021/ol501301w

Reference yield:

tert-butylchlorodiphenylsilane (58479-61-1) → tert-butyl(((Z)-4-(5-((E)-hex-3-en-1-yl)furan-2-yl)but-2-en-1-yl)oxy)diphenylsilane (1610935-36-8)

Guidance literature:

Multi-step reaction with 3 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / 0 °C

1.2: 3 h / 20 °C

2.1: phosphorus tribromide / diethyl ether / 0.17 h / 0 - 20 °C / Inert atmosphere

3.1: n-butyllithium / tetrahydrofuran; hexane / 0.33 h / 0 °C / Inert atmosphere

3.2: 4 h / 0 - 20 °C

With n-butyllithium; phosphorus tribromide; In tetrahydrofuran; diethyl ether; hexane;

DOI:10.1021/ol501301w

Reference yield:

(Z)-4-((tert-butyldiphenylsilyl)oxy)but-2-en-1-ol (87770-83-0) → tert-butyl(((Z)-4-(5-((E)-hex-3-en-1-yl)furan-2-yl)but-2-en-1-yl)oxy)diphenylsilane (1610935-36-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: phosphorus tribromide / diethyl ether / 0.17 h / 0 - 20 °C / Inert atmosphere

2.1: n-butyllithium / tetrahydrofuran; hexane / 0.33 h / 0 °C / Inert atmosphere

2.2: 4 h / 0 - 20 °C

With n-butyllithium; phosphorus tribromide; In tetrahydrofuran; diethyl ether; hexane;

DOI:10.1021/ol501301w

upstream raw materials:

(E)-2-(hex-3-en-1-yl)furan

(Z)-((4-bromobut-2-en-1-yl)oxy)(tert-butyl)diphenylsilane

tert-butylchlorodiphenylsilane

(Z)-4-((tert-butyldiphenylsilyl)oxy)but-2-en-1-ol