1,1-dimethylethyl 4-[4-(4,5-dihydro-5-phenyl-3-isoxazolyl)-2-thiazolyl]-1-piperazineacetate

Base Information

Chemical Name:1,1-dimethylethyl 4-[4-(4,5-dihydro-5-phenyl-3-isoxazolyl)-2-thiazolyl]-1-piperazineacetate
CAS No.:1148046-91-6
Molecular Formula:C₂₁H₂₆N₄O₃S
Molecular Weight:414.528
Hs Code.:

Synonyms:1,1-dimethylethyl 4-[4-(4,5-dihydro-5-phenyl-3-isoxazolyl)-2-thiazolyl]-1-piperazineacetate

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Chemical Property of 1,1-dimethylethyl 4-[4-(4,5-dihydro-5-phenyl-3-isoxazolyl)-2-thiazolyl]-1-piperazineacetate

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Technology Process of 1,1-dimethylethyl 4-[4-(4,5-dihydro-5-phenyl-3-isoxazolyl)-2-thiazolyl]-1-piperazineacetate

There total 2 articles about 1,1-dimethylethyl 4-[4-(4,5-dihydro-5-phenyl-3-isoxazolyl)-2-thiazolyl]-1-piperazineacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1003320-09-9
2-chloro-1-(4,5-dihydro-5-phenyl-3-isoxazolyl)ethanone

: 196811-66-2
4-(tert-butoxycarbonyl)piperazine-1-thiocarboxamide

: 1148046-91-6
1,1-dimethylethyl 4-[4-(4,5-dihydro-5-phenyl-3-isoxazolyl)-2-thiazolyl]-1-piperazineacetate

Guidance literature:: With triethylamine; In ethanol; at 20 ℃; for 12h;

Reference yield:

: C₁₃H₂₀N₄O₂S

: 1148046-91-6
1,1-dimethylethyl 4-[4-(4,5-dihydro-5-phenyl-3-isoxazolyl)-2-thiazolyl]-1-piperazineacetate

Guidance literature:: Multi-step reaction with 2 steps

1: ammonia / tetrahydrofuran; methanol / 24 h / 20 °C

2: triethylamine / ethanol / 12 h / 20 °C

With ammonia; triethylamine; In tetrahydrofuran; methanol; ethanol;