Methyl 3-amino-4-nitrothiophene-2-carboxylate

Base Information

Chemical Name:Methyl 3-amino-4-nitrothiophene-2-carboxylate
CAS No.:80621-56-3
Molecular Formula:C6H6 N2 O4 S
Molecular Weight:202.191
Hs Code.:2934999090
DSSTox Substance ID:DTXSID50513514
Wikidata:Q82373367
Mol file:80621-56-3.mol

Synonyms:Methyl 3-amino-4-nitrothiophene-2-carboxylate;80621-56-3;DTXSID50513514;Methyl3-amino-4-nitrothiophene-2-carboxylate

Suppliers and Price of Methyl 3-amino-4-nitrothiophene-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Methyl3-amino-4-nitrothiophene-2-carboxylate 95+%
1g
$ 772.00

Chemenu
methyl3-amino-4-nitrothiophene-2-carboxylate 95%
1g
$ 729.00

Arctom
Methyl3-amino-4-nitrothiophene-2-carboxylate
1g
$ 609.00

American Custom Chemicals Corporation
METHYL-3-AMINO-4-NITROTHIOPHENE-2-CARBOXYLATE 95.00%
5MG
$ 499.07

Total 5 raw suppliers

Chemical Property of Methyl 3-amino-4-nitrothiophene-2-carboxylate

Chemical Property:

PSA：126.38000
LogP:2.12950
Storage Temp.:2-8°C
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:202.00482785
Heavy Atom Count:13
Complexity:229

Purity/Quality:

98% ^*data from raw suppliers

Methyl3-amino-4-nitrothiophene-2-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=C(C(=CS1)[N+](=O)[O-])N

Technology Process of Methyl 3-amino-4-nitrothiophene-2-carboxylate

There total 3 articles about Methyl 3-amino-4-nitrothiophene-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 80615-53-8
methyl 3-acetamido-4-nitrothiophene-2-carboxylate

: 80621-56-3
methyl 3-amino-4-nitrothiophene-2-carboxylate

Guidance literature:: With sodium methylate; In methanol; at 55 - 60 ℃; for 1h;
DOI:10.1002/hlca.19980810103

Reference yield:

: 22288-79-5
3-acetylamine-2-thiophenecarboxylic acid methyl ester

: 80621-56-3
methyl 3-amino-4-nitrothiophene-2-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 35 percent / 95percent H₂SO₄-100percent HNO₃ / -25 - 0 °C

2: 80 percent / MeONa / methanol / 1 h / 55 - 60 °C

With sulfuric acid; nitric acid; sodium methylate; In methanol;
DOI:10.1002/hlca.19980810103

Reference yield:

: 22288-78-4
Methyl 3-aminothiophene-2-carboxylate

: 80621-56-3
methyl 3-amino-4-nitrothiophene-2-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: 6 h / 20 °C

2: sulfuric acid; nitric acid / -30 °C

3: sodium methylate / methanol / 8 h / 55 °C

With sulfuric acid; nitric acid; sodium methylate; In methanol;
DOI:10.3390/molecules21060772