(S)-N-[-4-[4-(3-aminopropylamino)-piperidino]-2-(3,4-dichlorophenyl)butyl]-N-methylbenzamide

Base Information

• Chemical Name: (S)-N-[-4-[4-(3-aminopropylamino)-piperidino]-2-(3,4-dichlorophenyl)butyl]-N-methylbenzamide
• CAS No.: 164519-07-7
• Molecular Formula: C₂₆H₃₆Cl₂N₄O
• Molecular Weight: 491.504
• Mol file: 164519-07-7.mol

Synonyms:(S)-N-[-4-[4-(3-aminopropylamino)-piperidino]-2-(3,4-dichlorophenyl)butyl]-N-methylbenzamide

Chemical Property of (S)-N-[-4-[4-(3-aminopropylamino)-piperidino]-2-(3,4-dichlorophenyl)butyl]-N-methylbenzamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-N-[-4-[4-(3-aminopropylamino)-piperidino]-2-(3,4-dichlorophenyl)butyl]-N-methylbenzamide

There total 2 articles about (S)-N-[-4-[4-(3-aminopropylamino)-piperidino]-2-(3,4-dichlorophenyl)butyl]-N-methylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-N-[2-(3,4-dichlorophenyl)-4-[4-[(2,2,2-trifluoroacetyl)[3-(2,2,2-trifluoroacetylamino)propyl]amino]-piperidino]butyl]-N-methylbenzamide (164519-11-3) → (S)-N-[-4-[4-(3-aminopropylamino)-piperidino]-2-(3,4-dichlorophenyl)butyl]-N-methylbenzamide (164519-07-7)

Guidance literature:

In methanol; aqueous potassium hydroxide;

Reference yield:

N-[2-(3,4-dichlorophenyl)-4-[4-[(2,2,2-trifluoroacetyl)[-3-(2,2,2-trifluoroacetylamino)propyl]amino]piperidino]butyl]-N-methylbenzamide → (S)-N-[-4-[4-(3-aminopropylamino)-piperidino]-2-(3,4-dichlorophenyl)butyl]-N-methylbenzamide (164519-07-7)

Guidance literature:

Reference yield:

(S)-N-[-4-[4-(3-aminopropylamino)-piperidino]-2-(3,4-dichlorophenyl)butyl]-N-methylbenzamide (164519-07-7) + 1,1'-carbonyldiimidazole (530-62-1) → (S)-N-[2-(3,4-Dichlorophenyl)-4-[4-(2-oxoperhydro-pyrimidin-1-yl)piperidino]butyl]-N-methylbenzamide dihydrochloride (164518-66-5)

Guidance literature:

In dichloromethane; chloroform;

upstream raw materials:

(S)-N-[2-(3,4-dichlorophenyl)-4-[4-[(2,2,2-trifluoroacetyl)[3-(2,2,2-trifluoroacetylamino)propyl]amino]-piperidino]butyl]-N-methylbenzamide

Downstream raw materials:

(S)-N-[2-(3,4-Dichlorophenyl)-4-[4-(2-oxoperhydro-pyrimidin-1-yl)piperidino]butyl]-N-methylbenzamide dihydrochloride