4-(4-bromophenyl)-6-trichloromethyl-2-phenyl-1,6-dihydropyrimidine

Base Information

• Chemical Name: 4-(4-bromophenyl)-6-trichloromethyl-2-phenyl-1,6-dihydropyrimidine
• CAS No.: 1450619-00-7
• Molecular Formula: C₁₇H₁₂BrCl₃N₂
• Molecular Weight: 430.559
• Mol file: 1450619-00-7.mol

Synonyms:4-(4-bromophenyl)-6-trichloromethyl-2-phenyl-1,6-dihydropyrimidine

Chemical Property of 4-(4-bromophenyl)-6-trichloromethyl-2-phenyl-1,6-dihydropyrimidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(4-bromophenyl)-6-trichloromethyl-2-phenyl-1,6-dihydropyrimidine

There total 1 articles about 4-(4-bromophenyl)-6-trichloromethyl-2-phenyl-1,6-dihydropyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

6-(4-bromophenyl)-6-hydroxy-2-phenyl-4-trichloromethyl-1,4,5,6-tetrahydropyrimidine → 4-(4-bromophenyl)-6-trichloromethyl-2-phenyl-1,6-dihydropyrimidine (1450619-00-7)

Guidance literature:

With sulfuric acid; In dichloromethane; for 12h; Reflux;

DOI:10.1016/j.tetlet.2013.07.075

Reference yield: 90.0%

4-(4-bromophenyl)-6-trichloromethyl-2-phenyl-1,6-dihydropyrimidine (1450619-00-7) → 4-(4-bromophenyl)-2-phenylpyrimidine (179329-51-2)

Guidance literature:

With potassium tert-butylate; In tetrahydrofuran; for 4h;

DOI:10.1016/j.tetlet.2013.07.075

Downstream raw materials:

4-(4-bromophenyl)-2-phenylpyrimidine