(2E)-N-5-isoquinolinyl-3-[4-(trifluoromethyl)phenyl]-2-butenamide hydrochloride

Base Information

• Chemical Name: (2E)-N-5-isoquinolinyl-3-[4-(trifluoromethyl)phenyl]-2-butenamide hydrochloride
• CAS No.: 581813-42-5
• Molecular Formula: C₂₀H₁₅F₃N₂O*ClH
• Molecular Weight: 392.808

Synonyms:(2E)-N-5-isoquinolinyl-3-[4-(trifluoromethyl)phenyl]-2-butenamide hydrochloride

Chemical Property of (2E)-N-5-isoquinolinyl-3-[4-(trifluoromethyl)phenyl]-2-butenamide hydrochloride

Chemical Property:

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Technology Process of (2E)-N-5-isoquinolinyl-3-[4-(trifluoromethyl)phenyl]-2-butenamide hydrochloride

There total 1 articles about (2E)-N-5-isoquinolinyl-3-[4-(trifluoromethyl)phenyl]-2-butenamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

isoquinolin-5-ylamine (1125-60-6) + (E)-3-(4-(trifluoromethyl)phenyl)but-2-enoyl chloride → N-5-isoquinolinyl-3-[4-(trifluoromethyl)phenyl]-3-butenamide (581811-05-4) + (2E)-N-5-isoquinolinyl-3-[4-(trifluoromethyl)phenyl]-2-butenamide hydrochloride (581813-42-5)

Guidance literature:

isoquinolin-5-ylamine; With sodium hydride; In N,N-dimethyl-formamide; for 0.75h;

(E)-3-(4-(trifluoromethyl)phenyl)but-2-enoyl chloride; In DMF (N,N-dimethyl-formamide); dichloromethane; for 0.25h;

upstream raw materials:

isoquinolin-5-ylamine

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