N-[4-(5-p-tolyl-3-trifluoromethyl-pyrazol-1-yl)-phenyl]-aminosulfonamide

Base Information

• Chemical Name: N-[4-(5-p-tolyl-3-trifluoromethyl-pyrazol-1-yl)-phenyl]-aminosulfonamide
• CAS No.: 1374744-71-4
• Molecular Formula: C₁₇H₁₅F₃N₄O₂S
• Molecular Weight: 396.393
• Mol file: 1374744-71-4.mol

Synonyms:N-[4-(5-p-tolyl-3-trifluoromethyl-pyrazol-1-yl)-phenyl]-aminosulfonamide

Chemical Property of N-[4-(5-p-tolyl-3-trifluoromethyl-pyrazol-1-yl)-phenyl]-aminosulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-[4-(5-p-tolyl-3-trifluoromethyl-pyrazol-1-yl)-phenyl]-aminosulfonamide

There total 4 articles about N-[4-(5-p-tolyl-3-trifluoromethyl-pyrazol-1-yl)-phenyl]-aminosulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C22H23F3N4O4S (1349221-71-1) → N-[4-(5-p-tolyl-3-trifluoromethyl-pyrazol-1-yl)-phenyl]-aminosulfonamide (1374744-71-4)

Guidance literature:

C₂₂H₂₃F₃N₄O₄S; With trifluoroacetic acid; In dichloromethane; for 1h;

With sodium hydrogencarbonate; In dichloromethane;

DOI:10.1016/j.bmc.2012.06.018

Reference yield:

4,4,4-trifluoro-1-(4-methylphenyl)butane-1,3-dione (720-94-5) → N-[4-(5-p-tolyl-3-trifluoromethyl-pyrazol-1-yl)-phenyl]-aminosulfonamide (1374744-71-4)

Guidance literature:

Multi-step reaction with 4 steps

1: hydrogenchloride / ethanol / Reflux

2: platinum(IV) oxide; hydrogen / ethanol

3: triethylamine / dichloromethane / 1 h / 25 °C

4: trifluoroacetic acid / dichloromethane / 1 h

With hydrogenchloride; platinum(IV) oxide; hydrogen; triethylamine; trifluoroacetic acid; In ethanol; dichloromethane;

DOI:10.1016/j.bmc.2012.06.018

Reference yield:

5-(4-methylphenyl)-1-(4-nitrophenyl)-3-trifluoromethylpyrazole (365530-10-5) → N-[4-(5-p-tolyl-3-trifluoromethyl-pyrazol-1-yl)-phenyl]-aminosulfonamide (1374744-71-4)

Guidance literature:

Multi-step reaction with 3 steps

1: platinum(IV) oxide; hydrogen / ethanol

2: triethylamine / dichloromethane / 1 h / 25 °C

3: trifluoroacetic acid / dichloromethane / 1 h

With platinum(IV) oxide; hydrogen; triethylamine; trifluoroacetic acid; In ethanol; dichloromethane;

DOI:10.1016/j.bmc.2012.06.018

upstream raw materials:

C₂₂H₂₃F₃N₄O₄S

4,4,4-trifluoro-1-(4-methylphenyl)butane-1,3-dione

5-(4-methylphenyl)-1-(4-nitrophenyl)-3-trifluoromethylpyrazole