Technology Process of 2,2'-dibromo-5,5'-diphenyl-4,4'-di-tert-butylbiphenyl
There total 2 articles about 2,2'-dibromo-5,5'-diphenyl-4,4'-di-tert-butylbiphenyl which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
2,2',5,5'-tetrabromo-4,4'-di-tert-butylbiphenyl;
With
tert.-butyl lithium;
In
tetrahydrofuran; pentane;
at -78 ℃;
for 2h;
With
zinc(II) chloride;
In
tetrahydrofuran; pentane;
at -78 - 20 ℃;
iodobenzene;
With
tetrakis(triphenylphosphine) palladium(0);
In
tetrahydrofuran; pentane;
at 100 ℃;
DOI:10.1016/S0040-4020(01)00241-1
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 23 percent / Br2; Fe / CCl4 / 6 h / 0 - 20 °C
2.1: t-BuLi / pentane; tetrahydrofuran / 2 h / -78 °C
2.2: ZnCl2 / tetrahydrofuran; pentane / -78 - 20 °C
2.3: 77 percent / Pd(PPh3)4 / tetrahydrofuran; pentane / 100 °C
With
bromine; tert.-butyl lithium; iron;
In
tetrahydrofuran; tetrachloromethane; pentane;
2.3: Negishi coupling;
DOI:10.1016/S0040-4020(01)00241-1
- Guidance literature:
-
2,2'-dibromo-5,5'-diphenyl-4,4'-di-tert-butylbiphenyl;
With
tert.-butyl lithium;
In
diethyl ether; pentane;
at -78 - -20 ℃;
With
copper(ll) bromide;
In
diethyl ether; pentane;
at -78 ℃;
for 2h;
DOI:10.1016/S0040-4020(01)00241-1
