1,2-Bis(5-methyl-2-phenyl-4-thiazolyl)perfluorocyclopentene

Base Information

Chemical Name:1,2-Bis(5-methyl-2-phenyl-4-thiazolyl)perfluorocyclopentene
CAS No.:210490-50-9
Molecular Formula:C₂₅H₁₆F₆N₂S₂
Molecular Weight:522.538
Hs Code.:
DSSTox Substance ID:DTXSID601348362
Nikkaji Number:J975.016I

Synonyms:1,2-bis(5-methyl-2-phenyl-4-thiazolyl)perfluorocyclopentene;SCHEMBL3434571;UTJFHXXSYPZEEJ-UHFFFAOYSA-N;DTXSID601348362;210490-50-9

Suppliers and Price of 1,2-Bis(5-methyl-2-phenyl-4-thiazolyl)perfluorocyclopentene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 0 raw suppliers

Chemical Property of 1,2-Bis(5-methyl-2-phenyl-4-thiazolyl)perfluorocyclopentene

Chemical Property:

XLogP3:7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:4
Exact Mass:522.06590984
Heavy Atom Count:35
Complexity:761

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C(N=C(S1)C2=CC=CC=C2)C3=C(C(C(C3(F)F)(F)F)(F)F)C4=C(SC(=N4)C5=CC=CC=C5)C

Technology Process of 1,2-Bis(5-methyl-2-phenyl-4-thiazolyl)perfluorocyclopentene

There total 8 articles about 1,2-Bis(5-methyl-2-phenyl-4-thiazolyl)perfluorocyclopentene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 943543-04-2
5-methyl-2-phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazolee

: 706-79-6
1,2-dichloro-3,3,4,4,5,5-hexafluorocyclopentene

: 210490-50-9
1,2-bis(5-methyl-2-phenyl-3-thiazolyl)-3,3,4,4,5,5-hexafluorocyclopentene

Guidance literature:: With tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; cesium fluoride; tricyclohexylphosphine; In water; toluene; for 16h; Inert atmosphere; Reflux;
DOI:10.1039/c1cc12020d

Reference yield: 52.0%

: 559-40-0
octaperfluorocyclopentene

: 210490-49-6
4-bromo-5-methyl-2-phenylthiazoline

: 210490-50-9
1,2-bis(5-methyl-2-phenyl-3-thiazolyl)-3,3,4,4,5,5-hexafluorocyclopentene

: 500004-36-4
4-(2,3,3,4,4,5,5-heptafluorocyclopentenyl)-5-methyl-2-phenylthiazole

Guidance literature:: 4-bromo-5-methyl-2-phenylthiazoline; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 1h;

octaperfluorocyclopentene; In tetrahydrofuran; hexane; at -78 ℃; for 2h; Further stages.;
DOI:10.1039/b702277h

Reference yield:

: 559-40-0
octaperfluorocyclopentene

: 210490-50-9
1,2-bis(5-methyl-2-phenyl-3-thiazolyl)-3,3,4,4,5,5-hexafluorocyclopentene

Guidance literature:: Multi-step reaction with 2 steps

1.1: butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C

1.2: 52 percent / tetrahydrofuran; hexane / 2 h / -78 °C

2.1: butyllithium / tetrahydrofuran; hexane / -78 °C

2.2: tetrahydrofuran; hexane / -78 °C

With n-butyllithium; In tetrahydrofuran; hexane;
DOI:10.1039/b702277h