(1R,3R)-3-Ethenyl-2,2-dimethylcyclopropane-1-carbonyl chloride

Base Information

Chemical Name:(1R,3R)-3-Ethenyl-2,2-dimethylcyclopropane-1-carbonyl chloride
CAS No.:84368-72-9
Molecular Formula:C₈H₁₁ClO
Molecular Weight:158.628
Hs Code.:
DSSTox Substance ID:DTXSID60564557
Mol file:84368-72-9.mol

Synonyms:84368-72-9;(1R,3R)-3-Ethenyl-2,2-dimethylcyclopropane-1-carbonyl chloride;SCHEMBL14210555;DTXSID60564557

Suppliers and Price of (1R,3R)-3-Ethenyl-2,2-dimethylcyclopropane-1-carbonyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of (1R,3R)-3-Ethenyl-2,2-dimethylcyclopropane-1-carbonyl chloride

Chemical Property:

PSA：17.07000
LogP:2.21000
XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:158.0498427
Heavy Atom Count:10
Complexity:184

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(C(C1C(=O)Cl)C=C)C
Isomeric SMILES:CC1([C@@H]([C@H]1C(=O)Cl)C=C)C

Technology Process of (1R,3R)-3-Ethenyl-2,2-dimethylcyclopropane-1-carbonyl chloride

There total 4 articles about (1R,3R)-3-Ethenyl-2,2-dimethylcyclopropane-1-carbonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 52454-70-3,52486-46-1,52486-48-3,52486-50-7,67528-57-8,67528-58-9,70371-62-9,104111-78-6
cis-2,2-Dimethyl-3-vinylcyclopropanecarboxylic acid

: 84368-72-9,83190-39-0
(1S,3R)-2,2-Dimethyl-3-vinyl-cyclopropanecarbonyl chloride

Guidance literature:: With oxalyl dichloride; In dichloromethane; for 1h;
DOI:10.1021/ja9537585

Reference yield:

: 66692-75-9
ethyl 3-formyl-2,2-dimethylcyclopropanecarboxylate

: 84368-72-9,83190-39-0
(1S,3R)-2,2-Dimethyl-3-vinyl-cyclopropanecarbonyl chloride

Guidance literature:: Multi-step reaction with 4 steps

1: 40 percent / methanol / 3 h / Heating

2: 93 percent / H₂O / dioxane / 2.5 h / Heating

3: 80 percent / tetrahydrofuran / 13 h / Ambient temperature

4: 85 percent / oxalyl chloride / CH₂Cl₂ / 1 h

With oxalyl dichloride; water; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane;
DOI:10.1021/ja9537585

Reference yield:

: 2102-46-7,26771-21-1,67528-54-5,72937-63-4,73611-02-6,79026-47-4,79082-71-6,99297-25-3
(rac)-cis-caronaldehyde

: 84368-72-9,83190-39-0
(1S,3R)-2,2-Dimethyl-3-vinyl-cyclopropanecarbonyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / tetrahydrofuran / 13 h / Ambient temperature

2: 85 percent / oxalyl chloride / CH₂Cl₂ / 1 h

With oxalyl dichloride; In tetrahydrofuran; dichloromethane;
DOI:10.1021/ja9537585