H-D-PHE-MET-ARG-PHE-NH2

Base Information

Chemical Name:H-D-PHE-MET-ARG-PHE-NH2
CAS No.:84313-42-8
Molecular Formula:C₂₉H₄₂N₈O₄S
Molecular Weight:598.77
Hs Code.:
Mol file:84313-42-8.mol

Synonyms:(D-PHE1)-FMRFAMIDE;[D-PHE1]-FMRFFAMIDE;D-PHE-MET-ARG-PHE AMIDE;D-PHE-MET-ARG-PHE-NH2;DF-M-R-F-NH2;H-D-PHE-MET-ARG-PHE-NH2;D-PHENYALANINE-METHIONINE-ARGININE-PHENYLALANINE AMIDE);neuropetide C [D-Phe1]

Suppliers and Price of H-D-PHE-MET-ARG-PHE-NH2

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of H-D-PHE-MET-ARG-PHE-NH2

Chemical Property:

PSA：243.61000
LogP:3.51940
Storage Temp.:−20°C

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of H-D-PHE-MET-ARG-PHE-NH2

There total 14 articles about H-D-PHE-MET-ARG-PHE-NH2 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 5241-58-7
L-Phenylalanine amide

: 123197-18-2
H-Phe-Met-Arg-OH

: 64190-70-1,84313-42-8,84413-35-4,84313-44-0
Neuropeptide C

Guidance literature:: With thermolysin; In methanol; for 3h; Product distribution; Ambient temperature; effect of the pH, conc. of MeOH, reaction time;
DOI:10.1248/cpb.36.4345

Reference yield: 67.0%

: 123197-28-4
Boc-Phe-Met-Arg(Mts)-Phe-NH₂

: 64190-70-1,84313-42-8,84413-35-4,84313-44-0
Neuropeptide C

Guidance literature:: With ethandithiol; trifluorormethanesulfonic acid; methyl-phenyl-thioether; In trifluoroacetic acid; for 1h;
DOI:10.1248/cpb.36.4345

Reference yield:

: 13734-34-4
N-tert-butoxycarbonyl-L-phenylalanine

: 64190-70-1,84313-42-8,84413-35-4,84313-44-0
Neuropeptide C

Guidance literature:: Multi-step reaction with 3 steps

1: 61 percent / N-methylmorpholine / dimethylformamide; tetrahydrofuran / 3 h

2: 89 percent / N-methylmorpholine, HOBt, DCC / dimethylformamide / 16 h

3: 67 percent / TFMSA-thioanisole, ethanedithiol / trifluoroacetic acid / 1 h

With 4-methyl-morpholine; ethandithiol; trifluorormethanesulfonic acid; methyl-phenyl-thioether; benzotriazol-1-ol; dicyclohexyl-carbodiimide; In tetrahydrofuran; N,N-dimethyl-formamide; trifluoroacetic acid;
DOI:10.1248/cpb.36.4345