2-(4-trifluoroacetamidophenyl)ethyl O-(6-O-benzoyl-2,3,4-tri-O-benzyl-L-glycero-α-D-manno-heptopyranosyl)-(1<*>3)-2,4,6,7-tetra-O-acetyl-L-glycero-α-D-manno-heptopyranoside

Base Information

Chemical Name:2-(4-trifluoroacetamidophenyl)ethyl O-(6-O-benzoyl-2,3,4-tri-O-benzyl-L-glycero-α-D-manno-heptopyranosyl)-(1<*>3)-2,4,6,7-tetra-O-acetyl-L-glycero-α-D-manno-heptopyranoside
CAS No.:158464-35-8
Molecular Formula:C₆₀H₆₄F₃NO₁₉
Molecular Weight:1160.16
Hs Code.:

2-(4-trifluoroacetamidophenyl)ethyl O-(6-O-benzoyl-2,3,4-tri-O-benzyl-L-glycero-α-D-manno-heptopyranosyl)-(1<*>3)-2,4,6,7-tetra-O-acetyl-L-glycero-α-D-manno-heptopyranoside

Synonyms:2-(4-trifluoroacetamidophenyl)ethyl O-(6-O-benzoyl-2,3,4-tri-O-benzyl-L-glycero-α-D-manno-heptopyranosyl)-(1<*>3)-2,4,6,7-tetra-O-acetyl-L-glycero-α-D-manno-heptopyranoside

Suppliers and Price of 2-(4-trifluoroacetamidophenyl)ethyl O-(6-O-benzoyl-2,3,4-tri-O-benzyl-L-glycero-α-D-manno-heptopyranosyl)-(1<*>3)-2,4,6,7-tetra-O-acetyl-L-glycero-α-D-manno-heptopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-(4-trifluoroacetamidophenyl)ethyl O-(6-O-benzoyl-2,3,4-tri-O-benzyl-L-glycero-α-D-manno-heptopyranosyl)-(1<*>3)-2,4,6,7-tetra-O-acetyl-L-glycero-α-D-manno-heptopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-(4-trifluoroacetamidophenyl)ethyl O-(6-O-benzoyl-2,3,4-tri-O-benzyl-L-glycero-α-D-manno-heptopyranosyl)-(1<*>3)-2,4,6,7-tetra-O-acetyl-L-glycero-α-D-manno-heptopyranoside

There total 5 articles about 2-(4-trifluoroacetamidophenyl)ethyl O-(6-O-benzoyl-2,3,4-tri-O-benzyl-L-glycero-α-D-manno-heptopyranosyl)-(1<*>3)-2,4,6,7-tetra-O-acetyl-L-glycero-α-D-manno-heptopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 158464-34-7
2-(4-trifluoroacetamidophenyl)ethyl O-(6-O-benzoyl-2,3,4-tri-O-benzyl-7-O-tert-butyldimethylsilyl-L-glycero-α-D-manno-heptopyranosyl)-(1<*>3)-2,4,6,7-tetra-O-acetyl-L-glycero-α-D-manno-heptopyranoside

: 158464-35-8
2-(4-trifluoroacetamidophenyl)ethyl O-(6-O-benzoyl-2,3,4-tri-O-benzyl-L-glycero-α-D-manno-heptopyranosyl)-(1<*>3)-2,4,6,7-tetra-O-acetyl-L-glycero-α-D-manno-heptopyranoside

Guidance literature:: With acetic acid; Ambient temperature;
DOI:10.1016/0008-6215(94)84244-2

Reference yield:

: 142270-25-5
2-(4-trifluoroacetamidophenyl)ethyl 6,7-di-O-acetyl-L-glycero-α-D-manno-heptopyranoside

: 158464-35-8
2-(4-trifluoroacetamidophenyl)ethyl O-(6-O-benzoyl-2,3,4-tri-O-benzyl-L-glycero-α-D-manno-heptopyranosyl)-(1<*>3)-2,4,6,7-tetra-O-acetyl-L-glycero-α-D-manno-heptopyranoside

Guidance literature:: Multi-step reaction with 5 steps

1: p-TsOH / acetonitrile / 0.5 h / Ambient temperature

2: pyridine, 4-dimethylaminopyridine / acetonitrile / 1 h / Ambient temperature

3: 90percent aq. TFA / acetonitrile / 0.5 h

4: 1.) dimethyl(methylthio)sulfonium triflate, 4A molecular sieves, 2.) Et₃N / 1.) Et₂O, RT, 2 h, 2.) Et₂O, 30 min

5: 96 percent / 70percent aq. AcOH / Ambient temperature

With pyridine; dmap; 4 A molecular sieve; toluene-4-sulfonic acid; acetic acid; dimethyl-(methylthio)-sulphonium trifluoromethanesulphonate; triethylamine; trifluoroacetic acid; In acetonitrile;
DOI:10.1016/0008-6215(94)84244-2

Reference yield:

: Acetic acid (S)-2-acetoxy-1-((3aS,4S,6S,7R,7aS)-7-hydroxy-2-methoxy-2-methyl-4-{2-[4-(2,2,2-trifluoro-acetylamino)-phenyl]-ethoxy}-tetrahydro-[1,3]dioxolo[4,5-c]pyran-6-yl)-ethyl ester

: 158464-35-8
2-(4-trifluoroacetamidophenyl)ethyl O-(6-O-benzoyl-2,3,4-tri-O-benzyl-L-glycero-α-D-manno-heptopyranosyl)-(1<*>3)-2,4,6,7-tetra-O-acetyl-L-glycero-α-D-manno-heptopyranoside

Guidance literature:: Multi-step reaction with 4 steps

1: pyridine, 4-dimethylaminopyridine / acetonitrile / 1 h / Ambient temperature

2: 90percent aq. TFA / acetonitrile / 0.5 h

3: 1.) dimethyl(methylthio)sulfonium triflate, 4A molecular sieves, 2.) Et₃N / 1.) Et₂O, RT, 2 h, 2.) Et₂O, 30 min

4: 96 percent / 70percent aq. AcOH / Ambient temperature

With pyridine; dmap; 4 A molecular sieve; acetic acid; dimethyl-(methylthio)-sulphonium trifluoromethanesulphonate; triethylamine; trifluoroacetic acid; In acetonitrile;
DOI:10.1016/0008-6215(94)84244-2