(1,1-diethoxy-ethyl)-(4-chloro-phenyl)-phosphinic acid ethyl ester

Base Information

• Chemical Name: (1,1-diethoxy-ethyl)-(4-chloro-phenyl)-phosphinic acid ethyl ester
• CAS No.: 23081-58-5
• Molecular Formula: C₁₄H₂₂ClO₄P
• Molecular Weight: 320.753
• Mol file: 23081-58-5.mol

Synonyms:(1,1-diethoxy-ethyl)-(4-chloro-phenyl)-phosphinic acid ethyl ester

Chemical Property of (1,1-diethoxy-ethyl)-(4-chloro-phenyl)-phosphinic acid ethyl ester

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of (1,1-diethoxy-ethyl)-(4-chloro-phenyl)-phosphinic acid ethyl ester

There total 2 articles about (1,1-diethoxy-ethyl)-(4-chloro-phenyl)-phosphinic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

(4-chlorophenyl)phosphinic acid (22336-21-6) + Triethyl orthoacetate (78-39-7) → (1,1-diethoxy-ethyl)-(4-chloro-phenyl)-phosphinic acid ethyl ester (23081-58-5)

Guidance literature:

With boron trifluoride diethyl etherate; at 20 ℃; for 24h; Inert atmosphere;

DOI:10.1002/ejoc.200900694

Reference yield:

Triethyl orthoacetate (78-39-7) + C8H9Cl2OP → (1,1-diethoxy-ethyl)-(4-chloro-phenyl)-phosphinic acid ethyl ester (23081-58-5)

Guidance literature:

Reference yield: 52.0%

(1,1-diethoxy-ethyl)-(4-chloro-phenyl)-phosphinic acid ethyl ester (23081-58-5) + aniline (62-53-3) → (1,1-diethoxy-ethyl)-(4-phenylamino-phenyl)-phosphinic acid ethyl ester

Guidance literature:

With potassium phosphate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; DavePhos; In 1,2-dimethoxyethane; at 20 - 100 ℃; for 24h;

DOI:10.1002/ejoc.200900694

upstream raw materials:

Triethyl orthoacetate

(4-chlorophenyl)phosphinic acid