N-{2-[3-(4-fluorophenyl)[1,2,4]oxadiazol-5-yl]cyclopenten-1-yl}formamide oxime

Base Information

Chemical Name:N-{2-[3-(4-fluorophenyl)[1,2,4]oxadiazol-5-yl]cyclopenten-1-yl}formamide oxime
CAS No.:457072-23-0
Molecular Formula:C₁₄H₁₃FN₄O₂
Molecular Weight:288.281
Hs Code.:

Synonyms:N-{2-[3-(4-fluorophenyl)[1,2,4]oxadiazol-5-yl]cyclopenten-1-yl}formamide oxime

Suppliers and Price of N-{2-[3-(4-fluorophenyl)[1,2,4]oxadiazol-5-yl]cyclopenten-1-yl}formamide oxime

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-{2-[3-(4-fluorophenyl)[1,2,4]oxadiazol-5-yl]cyclopenten-1-yl}formamide oxime

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Technology Process of N-{2-[3-(4-fluorophenyl)[1,2,4]oxadiazol-5-yl]cyclopenten-1-yl}formamide oxime

There total 2 articles about N-{2-[3-(4-fluorophenyl)[1,2,4]oxadiazol-5-yl]cyclopenten-1-yl}formamide oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 457072-56-9
N₁,N₁-dimethyl-N₂-(6,7-dihydro-5H-cyclopenta[1,2-d]pyrimidin-4-yl)-4-fluorobenzamidine

: 457072-23-0
N-{2-[3-(4-fluorophenyl)[1,2,4]oxadiazol-5-yl]cyclopenten-1-yl}formamide oxime

Guidance literature:: With hydroxylamine hydrochloride; In methanol; at 20 ℃; for 6h;
DOI:10.1002/jhet.564

Reference yield:

: 26979-06-6
4-amino-6,7-dihydro-5H-cyclopenta[1,2-d]pyrimidine

: 24167-56-4
N,N-dimethyl-4-fluorobenzamide

: 457072-23-0
N-{2-[3-(4-fluorophenyl)[1,2,4]oxadiazol-5-yl]cyclopenten-1-yl}formamide oxime

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine; trichlorophosphate / chloroform / 20 h / Reflux

2: hydroxylamine hydrochloride / methanol / 6 h / 20 °C

With hydroxylamine hydrochloride; triethylamine; trichlorophosphate; In methanol; chloroform;
DOI:10.1002/jhet.564