methyl 1-{4-[2-(3-chloro-4-fluorophenyl)-1H-benzimidazol-1-yl]piperidin-1-yl}cyclohexanecarboxylate

Base Information

Chemical Name:methyl 1-{4-[2-(3-chloro-4-fluorophenyl)-1H-benzimidazol-1-yl]piperidin-1-yl}cyclohexanecarboxylate
CAS No.:1258305-01-9
Molecular Formula:C₂₆H₂₉ClFN₃O₂
Molecular Weight:469.987
Hs Code.:

Synonyms:methyl 1-{4-[2-(3-chloro-4-fluorophenyl)-1H-benzimidazol-1-yl]piperidin-1-yl}cyclohexanecarboxylate

Suppliers and Price of methyl 1-{4-[2-(3-chloro-4-fluorophenyl)-1H-benzimidazol-1-yl]piperidin-1-yl}cyclohexanecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 1-{4-[2-(3-chloro-4-fluorophenyl)-1H-benzimidazol-1-yl]piperidin-1-yl}cyclohexanecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 1-{4-[2-(3-chloro-4-fluorophenyl)-1H-benzimidazol-1-yl]piperidin-1-yl}cyclohexanecarboxylate

There total 1 articles about methyl 1-{4-[2-(3-chloro-4-fluorophenyl)-1H-benzimidazol-1-yl]piperidin-1-yl}cyclohexanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1258305-00-8
C₂₆H₃₁ClFN₃O₃

: 1258305-01-9
methyl 1-{4-[2-(3-chloro-4-fluorophenyl)-1H-benzimidazol-1-yl]piperidin-1-yl}cyclohexanecarboxylate

Guidance literature:: C₂₆H₃₁ClFN₃O₃; With trichlorophosphate; at 110 - 120 ℃; Inert atmosphere;

With ammonia; In chloroform; water; at 0 ℃;
DOI:10.1016/j.bmc.2010.07.034

Reference yield: 68.0%

: 1258305-01-9
methyl 1-{4-[2-(3-chloro-4-fluorophenyl)-1H-benzimidazol-1-yl]piperidin-1-yl}cyclohexanecarboxylate

: 1258305-02-0
(1-{4-[2-(3-chloro-4-fluorophenyl)-1H-benzimidazol-1-yl]piperidin-1-yl}cyclohexyl)methanol

Guidance literature:: methyl 1-{4-[2-(3-chloro-4-fluorophenyl)-1H-benzimidazol-1-yl]piperidin-1-yl}cyclohexanecarboxylate; With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃; for 48h; Inert atmosphere;

With water; In tetrahydrofuran; ethyl acetate; at 0 - 20 ℃; for 1h;
DOI:10.1016/j.bmc.2010.07.034