Carbamic acid, N-(2-phenoxyethyl)-N-2-propen-1-yl-, 1,1-dimethylethyl ester

Base Information

Chemical Name:Carbamic acid, N-(2-phenoxyethyl)-N-2-propen-1-yl-, 1,1-dimethylethyl ester
CAS No.:1313189-40-0
Molecular Formula:C₁₆H₂₃NO₃
Molecular Weight:277.364
Hs Code.:
DSSTox Substance ID:DTXSID401143401

Synonyms:DTXSID401143401;Carbamic acid, N-(2-phenoxyethyl)-N-2-propen-1-yl-, 1,1-dimethylethyl ester;1313189-40-0

Suppliers and Price of Carbamic acid, N-(2-phenoxyethyl)-N-2-propen-1-yl-, 1,1-dimethylethyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Carbamic acid, N-(2-phenoxyethyl)-N-2-propen-1-yl-, 1,1-dimethylethyl ester

Chemical Property:

XLogP3:3.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:8
Exact Mass:277.16779360
Heavy Atom Count:20
Complexity:303

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N(CCOC1=CC=CC=C1)CC=C

Technology Process of Carbamic acid, N-(2-phenoxyethyl)-N-2-propen-1-yl-, 1,1-dimethylethyl ester

There total 1 articles about Carbamic acid, N-(2-phenoxyethyl)-N-2-propen-1-yl-, 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 921596-28-3
tert-butyl (2-phenoxyethyl)carbamate

: 106-95-6
allyl bromide

: 1313189-40-0
tert-butyl N-(2-phenoxyethyl)-N-prop-2-enylcarbamate

Guidance literature:: tert-butyl (2-phenoxyethyl)carbamate; With potassium hydride; In tetrahydrofuran; mineral oil; at 20 ℃; for 0.166667h; Inert atmosphere;

allyl bromide; In tetrahydrofuran; mineral oil; at 0 ℃; for 3h; Inert atmosphere;
DOI:10.1002/ejoc.201100166

Reference yield: 95.0%

: 1313189-40-0
tert-butyl N-(2-phenoxyethyl)-N-prop-2-enylcarbamate

: 1313189-41-1
tert-butyl N-(3-hydroxypropyl)-N-(2-phenoxyethyl)carbamate

Guidance literature:: tert-butyl N-(2-phenoxyethyl)-N-prop-2-enylcarbamate; With 9-bora-bicyclo[3.3.1]nonane; In tetrahydrofuran; at 0 - 20 ℃; for 21h; Inert atmosphere;

With dihydrogen peroxide; sodium hydroxide; In tetrahydrofuran; water; at 50 ℃; for 2h; Inert atmosphere;
DOI:10.1002/ejoc.201100166

Reference yield:

: 1313189-40-0
tert-butyl N-(2-phenoxyethyl)-N-prop-2-enylcarbamate

: 1313189-46-6
tert-butyl N-(3-hydroxypropyl)-N-[2-[4-(5-iodothiophen-2-yl)phenoxy]ethyl]carbamate

Guidance literature:: Multi-step reaction with 6 steps

1.1: 9-bora-bicyclo[3.3.1]nonane / tetrahydrofuran / 21 h / 0 - 20 °C / Inert atmosphere

1.2: 2 h / 50 °C / Inert atmosphere

2.1: 1H-imidazole / N,N-dimethyl-formamide / 0 - 20 °C / Inert atmosphere

3.1: iodine; bis-[(trifluoroacetoxy)iodo]benzene / chloroform / 0 - 20 °C / Inert atmosphere

4.1: sodium carbonate; triphenylphosphine; bis(dibenzylideneacetone)-palladium⁽⁰⁾ / tetrahydrofuran / 12 h / 75 °C / Inert atmosphere

5.1: potassium acetate; Iodine monochloride; acetic acid / 0 - 50 °C / Inert atmosphere

6.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 2 h / 20 °C / Inert atmosphere

With 1H-imidazole; tetrabutyl ammonium fluoride; iodine; potassium acetate; Iodine monochloride; sodium carbonate; acetic acid; 9-bora-bicyclo[3.3.1]nonane; triphenylphosphine; bis-[(trifluoroacetoxy)iodo]benzene; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In tetrahydrofuran; chloroform; N,N-dimethyl-formamide; 4.1: Suzuki coupling;
DOI:10.1002/ejoc.201100166