ethanesulfonic acid ((2S)-3-{2-ethyl-4-[5-(5-isobutyl-4-methyl-pyridin-2-yl)-[1,2,4]oxadiazol-3-yl]-6-methyl-phenoxy}-2-hydroxy-propyl)-amide

Base Information

Chemical Name:ethanesulfonic acid ((2S)-3-{2-ethyl-4-[5-(5-isobutyl-4-methyl-pyridin-2-yl)-[1,2,4]oxadiazol-3-yl]-6-methyl-phenoxy}-2-hydroxy-propyl)-amide
CAS No.:1186606-37-0
Molecular Formula:C₂₆H₃₆N₄O₅S
Molecular Weight:516.662
Hs Code.:

Synonyms:ethanesulfonic acid ((2S)-3-{2-ethyl-4-[5-(5-isobutyl-4-methyl-pyridin-2-yl)-[1,2,4]oxadiazol-3-yl]-6-methyl-phenoxy}-2-hydroxy-propyl)-amide

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Chemical Property of ethanesulfonic acid ((2S)-3-{2-ethyl-4-[5-(5-isobutyl-4-methyl-pyridin-2-yl)-[1,2,4]oxadiazol-3-yl]-6-methyl-phenoxy}-2-hydroxy-propyl)-amide

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Technology Process of ethanesulfonic acid ((2S)-3-{2-ethyl-4-[5-(5-isobutyl-4-methyl-pyridin-2-yl)-[1,2,4]oxadiazol-3-yl]-6-methyl-phenoxy}-2-hydroxy-propyl)-amide

There total 2 articles about ethanesulfonic acid ((2S)-3-{2-ethyl-4-[5-(5-isobutyl-4-methyl-pyridin-2-yl)-[1,2,4]oxadiazol-3-yl]-6-methyl-phenoxy}-2-hydroxy-propyl)-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: ethanesulfonamide potassium salt

: 1186606-35-8
2-[3-((S)-3-ethyl-5-methyl-4-oxiranylmethoxy-phenyl)-[1,2,4]oxadiazol-5-yl]-5-isobutyl-4-methyl-pyridine

: 1186606-37-0
ethanesulfonic acid ((2S)-3-{2-ethyl-4-[5-(5-isobutyl-4-methyl-pyridin-2-yl)-[1,2,4]oxadiazol-3-yl]-6-methyl-phenoxy}-2-hydroxy-propyl)-amide

Guidance literature:: In N,N-dimethyl-formamide; at 60 ℃; for 18h;

Reference yield:

: 1186606-10-9
2-ethyl-4-[5-(5-isobutyl-4-methyl-pyridin-2-yl)-[1,2,4]oxadiazol-3-yl]-6-methyl-phenol

: 1186606-37-0
ethanesulfonic acid ((2S)-3-{2-ethyl-4-[5-(5-isobutyl-4-methyl-pyridin-2-yl)-[1,2,4]oxadiazol-3-yl]-6-methyl-phenoxy}-2-hydroxy-propyl)-amide

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide / water; isopropyl alcohol / 42 h / 20 °C

2: N,N-dimethyl-formamide / 18 h / 60 °C

With sodium hydroxide; In water; N,N-dimethyl-formamide; isopropyl alcohol;