naphtho[2,1-b]thiophen-1(2H)-one

Base Information

Chemical Name:naphtho[2,1-b]thiophen-1(2H)-one
CAS No.:82-60-0
Molecular Formula:C12H8 O S
Molecular Weight:200.25632
Hs Code.:
DSSTox Substance ID:DTXSID30479240
Wikidata:Q82313221
Mol file:82-60-0.mol

Synonyms:naphtho[2,1-b]thiophen-1(2H)-one;benzo[e][1]benzothiol-1-one;82-60-0;SCHEMBL87603;DTXSID30479240

Suppliers and Price of naphtho[2,1-b]thiophen-1(2H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of naphtho[2,1-b]thiophen-1(2H)-one

Chemical Property:

PSA：42.37000
LogP:3.12820
XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:200.02958605
Heavy Atom Count:14
Complexity:251

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(=O)C2=C(S1)C=CC3=CC=CC=C32

Technology Process of naphtho[2,1-b]thiophen-1(2H)-one

There total 11 articles about naphtho[2,1-b]thiophen-1(2H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 93-21-0
(2-naphthylthio)acetic acid

: 82-60-0
naphtho[2,1-b]thiophen-1-ol

Guidance literature:: With chlorosulfonic acid; chloroform;

Reference yield:

: 866784-11-4
2-methylsulfanyl-naphthalene-1-carboxylic acid diethylamide

: 82-60-0
naphtho[2,1-b]thiophen-1-ol

Guidance literature:: With lithium diisopropyl amide; In tetrahydrofuran; at -78 - 20 ℃;
DOI:10.1016/j.tet.2005.07.050

Reference yield:

: 86-55-5
1-naphthalenecarboxylic acid

: 82-60-0
naphtho[2,1-b]thiophen-1-ol

Guidance literature:: Multi-step reaction with 3 steps

1.1: SOCl₂ / benzene / Heating

1.2: benzene / 20 °C

2.1: s-BuLi; TMEDA / tetrahydrofuran

3.1: LDA / tetrahydrofuran / -78 - 20 °C

With thionyl chloride; N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; lithium diisopropyl amide; In tetrahydrofuran; benzene;
DOI:10.1016/j.tet.2005.07.050