3-(4-chloro-phenyl)-1-{1-[2-(4-chloro-phenyl)-2-oxo-ethyl]-1H-benzoimidazol-2-yl}-propenone

Base Information

Chemical Name:3-(4-chloro-phenyl)-1-{1-[2-(4-chloro-phenyl)-2-oxo-ethyl]-1H-benzoimidazol-2-yl}-propenone
CAS No.:472962-78-0
Molecular Formula:C₂₄H₁₆Cl₂N₂O₂
Molecular Weight:435.309
Hs Code.:

3-(4-chloro-phenyl)-1-{1-[2-(4-chloro-phenyl)-2-oxo-ethyl]-1<i>H</i>-benzoimidazol-2-yl}-propenone

Synonyms:3-(4-chloro-phenyl)-1-{1-[2-(4-chloro-phenyl)-2-oxo-ethyl]-1H-benzoimidazol-2-yl}-propenone

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Chemical Property of 3-(4-chloro-phenyl)-1-{1-[2-(4-chloro-phenyl)-2-oxo-ethyl]-1H-benzoimidazol-2-yl}-propenone

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Technology Process of 3-(4-chloro-phenyl)-1-{1-[2-(4-chloro-phenyl)-2-oxo-ethyl]-1H-benzoimidazol-2-yl}-propenone

There total 3 articles about 3-(4-chloro-phenyl)-1-{1-[2-(4-chloro-phenyl)-2-oxo-ethyl]-1H-benzoimidazol-2-yl}-propenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 536-38-9
4-chlorobenzoylmethyl bromide

: 472962-73-5
(E)-1-(1H-benzo[d]imidazol-2-yl)-3-(4-chlorophenyl)prop-2-en-1-one

: 472962-78-0
3-(4-chloro-phenyl)-1-{1-[2-(4-chloro-phenyl)-2-oxo-ethyl]-1H-benzoimidazol-2-yl}-propenone

Guidance literature:: With potassium carbonate; In acetone; at 20 ℃; for 6h;
DOI:10.1016/S0223-5234(01)01313-7

Reference yield:

: 104-88-1
4-chlorobenzaldehyde

: 472962-78-0
3-(4-chloro-phenyl)-1-{1-[2-(4-chloro-phenyl)-2-oxo-ethyl]-1H-benzoimidazol-2-yl}-propenone

Guidance literature:: Multi-step reaction with 2 steps

1: 82 percent / K₂CO₃ / acetone / 6 h / 20 °C

With potassium carbonate; In acetone;
DOI:10.1016/S0223-5234(01)01313-7

Reference yield:

: 939-70-8
2-acetylbenzimidazole

: 472962-78-0
3-(4-chloro-phenyl)-1-{1-[2-(4-chloro-phenyl)-2-oxo-ethyl]-1H-benzoimidazol-2-yl}-propenone

Guidance literature:: Multi-step reaction with 2 steps

1: 82 percent / K₂CO₃ / acetone / 6 h / 20 °C

With potassium carbonate; In acetone;
DOI:10.1016/S0223-5234(01)01313-7