<7-(Tetrahydro-2-pyranyloxy)heptyl>-triphenylphosphonium-bromid

Base Information

• Chemical Name: <7-(Tetrahydro-2-pyranyloxy)heptyl>-triphenylphosphonium-bromid
• CAS No.: 79837-76-6
• Molecular Formula: Br*C₃₀H₃₈O₂P
• Molecular Weight: 541.508
• Mol file: 79837-76-6.mol

Synonyms:<7-(Tetrahydro-2-pyranyloxy)heptyl>-triphenylphosphonium-bromid

Chemical Property of <7-(Tetrahydro-2-pyranyloxy)heptyl>-triphenylphosphonium-bromid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of <7-(Tetrahydro-2-pyranyloxy)heptyl>-triphenylphosphonium-bromid

There total 4 articles about <7-(Tetrahydro-2-pyranyloxy)heptyl>-triphenylphosphonium-bromid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

7-bromo-1-(2-tetrahydropyranyloxy)heptane (10160-25-5) + triphenylphosphine (603-35-0) → <7-(Tetrahydro-2-pyranyloxy)heptyl>-triphenylphosphonium-bromid (79837-76-6)

Guidance literature:

In acetonitrile; for 48h; Heating;

DOI:10.1002/jlac.198119810920

Reference yield:

7-bromoheptyl alcohol (10160-24-4) → <7-(Tetrahydro-2-pyranyloxy)heptyl>-triphenylphosphonium-bromid (79837-76-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 94 percent / p-TsOH / 1,2-dichloro-ethane / 4 h / 20 °C

2: 1 h / 120 °C

With toluene-4-sulfonic acid; In 1,2-dichloro-ethane;

DOI:10.1016/S0968-0896(02)00138-4

Reference yield:

3,4-dihydro-2H-pyran (110-87-2) → <7-(Tetrahydro-2-pyranyloxy)heptyl>-triphenylphosphonium-bromid (79837-76-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 94 percent / p-TsOH / 1,2-dichloro-ethane / 4 h / 20 °C

2: 1 h / 120 °C

With toluene-4-sulfonic acid; In 1,2-dichloro-ethane;

DOI:10.1016/S0968-0896(02)00138-4

upstream raw materials:

7-bromo-1-(2-tetrahydropyranyloxy)heptane

triphenylphosphine

3,4-dihydro-2H-pyran

7-bromoheptyl alcohol