(R)-2,2,2-trifluoro-N-(4-methoxyphenyl)-N-(1-phenethyl-1-methyl-1-allyl)acetamid

Base Information

Chemical Name:(R)-2,2,2-trifluoro-N-(4-methoxyphenyl)-N-(1-phenethyl-1-methyl-1-allyl)acetamid
CAS No.:960060-59-7
Molecular Formula:C₂₁H₂₂F₃NO₂
Molecular Weight:377.406
Hs Code.:

Synonyms:(R)-2,2,2-trifluoro-N-(4-methoxyphenyl)-N-(1-phenethyl-1-methyl-1-allyl)acetamid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-2,2,2-trifluoro-N-(4-methoxyphenyl)-N-(1-phenethyl-1-methyl-1-allyl)acetamid

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Technology Process of (R)-2,2,2-trifluoro-N-(4-methoxyphenyl)-N-(1-phenethyl-1-methyl-1-allyl)acetamid

There total 2 articles about (R)-2,2,2-trifluoro-N-(4-methoxyphenyl)-N-(1-phenethyl-1-methyl-1-allyl)acetamid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: (E)-2,2,2-trifluoro-N-(4-methoxyphenyl)acetimidic acid 3-methyl-5-phenylpent-2-enyl ester

: 960060-59-7
(R)-2,2,2-trifluoro-N-(4-methoxyphenyl)-N-(1-phenethyl-1-methyl-1-allyl)acetamid

Guidance literature:: With silver trifluoroacetate; N,N,N',N'-tetramethyl-1,8-diaminonaphthalene; ferrocenyl 1-Ts-2,3-Ph₂-imidazoline palladacycle catalyst; In dichloromethane; at 50 ℃; for 60h;
DOI:10.1002/anie.200702086

Reference yield: 94.0%

: 960060-45-1
(E)-2,2,2-trifluoro-N-(4-methoxyphenyl)acetimidic acid 3-methyl-5-phenyl-pent-2-enyl ester

: 960060-59-7
(R)-2,2,2-trifluoro-N-(4-methoxyphenyl)-N-(1-phenethyl-1-methyl-1-allyl)acetamid

Guidance literature:: With di-μ-chlorobis[η⁵-(4'R,5'R)-(S_p)-2-(2'-4',5'-dihydro-4',5'-diphenyl-1'-tosyl-1'H-imidazolyl)cyclopentadienyl, (1-C,3'-N)(η⁵-pentaphenylcyclopentadienyl)-iron(II)]dipalladium(II); silver trifluoroacetate; N,N,N',N'-tetramethyl-1,8-diaminonaphthalene; In dichloromethane; at 50 ℃; for 60h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;
DOI:10.1002/chem.200900712