(3S,7R,7aR)-2,2-Dimethyl-5-oxo-7-phenylacetylamino-hexahydro-imidazo[5,1-b]thiazole-3-carboxylic acid methoxymethyl ester

Base Information

• Chemical Name: (3S,7R,7aR)-2,2-Dimethyl-5-oxo-7-phenylacetylamino-hexahydro-imidazo[5,1-b]thiazole-3-carboxylic acid methoxymethyl ester
• CAS No.: 104430-25-3
• Molecular Formula: C₁₈H₂₃N₃O₅S
• Molecular Weight: 393.464
• Mol file: 104430-25-3.mol

Synonyms:(3S,7R,7aR)-2,2-Dimethyl-5-oxo-7-phenylacetylamino-hexahydro-imidazo[5,1-b]thiazole-3-carboxylic acid methoxymethyl ester

Chemical Property of (3S,7R,7aR)-2,2-Dimethyl-5-oxo-7-phenylacetylamino-hexahydro-imidazo[5,1-b]thiazole-3-carboxylic acid methoxymethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of (3S,7R,7aR)-2,2-Dimethyl-5-oxo-7-phenylacetylamino-hexahydro-imidazo[5,1-b]thiazole-3-carboxylic acid methoxymethyl ester

There total 1 articles about (3S,7R,7aR)-2,2-Dimethyl-5-oxo-7-phenylacetylamino-hexahydro-imidazo[5,1-b]thiazole-3-carboxylic acid methoxymethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2R,4S)-2-((R)-Hydroxycarbamoyl-phenylacetylamino-methyl)-5,5-dimethyl-thiazolidine-4-carboxylic acid methoxymethyl ester (104430-20-8) → (3S,7R,7aR)-2,2-Dimethyl-5-oxo-7-phenylacetylamino-hexahydro-imidazo[5,1-b]thiazole-3-carboxylic acid methoxymethyl ester (104430-25-3)

Guidance literature:

With ynamine; In dichloromethane; 1.) 0 deg C to 20 deg C for 1 h, 2.) room temperature, 4 h;

DOI:10.1002/bscb.19850941123

Reference yield: 90.0%

(3S,7R,7aR)-2,2-Dimethyl-5-oxo-7-phenylacetylamino-hexahydro-imidazo[5,1-b]thiazole-3-carboxylic acid methoxymethyl ester (104430-25-3) → (3S,7R,7aR)-2,2-Dimethyl-5-oxo-7-phenylacetylamino-hexahydro-imidazo[5,1-b]thiazole-3-carboxylic acid (104430-29-7)

Guidance literature:

With hydrogenchloride; In ethanol; for 2h; Heating;

DOI:10.1002/bscb.19850941123

upstream raw materials:

(2R,4S)-2-((R)-Hydroxycarbamoyl-phenylacetylamino-methyl)-5,5-dimethyl-thiazolidine-4-carboxylic acid methoxymethyl ester

Downstream raw materials:

(3S,7R,7aR)-2,2-Dimethyl-5-oxo-7-phenylacetylamino-hexahydro-imidazo[5,1-b]thiazole-3-carboxylic acid