tert-butyl 5-amino-2-methylthio-4-(3-(vinylsulfonamido)-phenyl)-thieno[2,3-d]pyrimidine-6-carboxamide

Base Information

Chemical Name:tert-butyl 5-amino-2-methylthio-4-(3-(vinylsulfonamido)-phenyl)-thieno[2,3-d]pyrimidine-6-carboxamide
CAS No.:405890-99-5
Molecular Formula:C₂₀H₂₃N₅O₃S₃
Molecular Weight:477.632
Hs Code.:

Synonyms:tert-butyl 5-amino-2-methylthio-4-(3-(vinylsulfonamido)-phenyl)-thieno[2,3-d]pyrimidine-6-carboxamide

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Chemical Property of tert-butyl 5-amino-2-methylthio-4-(3-(vinylsulfonamido)-phenyl)-thieno[2,3-d]pyrimidine-6-carboxamide

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Technology Process of tert-butyl 5-amino-2-methylthio-4-(3-(vinylsulfonamido)-phenyl)-thieno[2,3-d]pyrimidine-6-carboxamide

There total 1 articles about tert-butyl 5-amino-2-methylthio-4-(3-(vinylsulfonamido)-phenyl)-thieno[2,3-d]pyrimidine-6-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 301847-69-8
5-amino-4-(3-aminophenyl)-N-(tert-butyl)-2-(methylthio)thieno[2,3-d]pyrimidine-6-carboxamide

: 54429-56-0
2-bromoethanesulfonyl chloride

: 405890-99-5
tert-butyl 5-amino-2-methylthio-4-(3-(vinylsulfonamido)-phenyl)-thieno[2,3-d]pyrimidine-6-carboxamide

Guidance literature:: With pyridine; In dichloromethane; at 20 ℃; for 2h;

Reference yield:

: 110-89-4
piperidine

: 405890-99-5
tert-butyl 5-amino-2-methylthio-4-(3-(vinylsulfonamido)-phenyl)-thieno[2,3-d]pyrimidine-6-carboxamide

: 76-05-1
trifluoroacetic acid

: tert-butyl 5-amino-2-methylthio-4-(3-(2-piperidinoethanesulfonamido)-phenyl)-thieno[2,3-d]pyrimidine-6-carboxamide trifluoroacetic acid salt

Guidance literature:: piperidine; tert-butyl 5-amino-2-methylthio-4-(3-(vinylsulfonamido)-phenyl)-thieno[2,3-d]pyrimidine-6-carboxamide; In tetrahydrofuran; at 20 ℃;

trifluoroacetic acid; In 1,4-dioxane; water;

Reference yield:

: 109-01-3
1-methyl-piperazine

: 405890-99-5
tert-butyl 5-amino-2-methylthio-4-(3-(vinylsulfonamido)-phenyl)-thieno[2,3-d]pyrimidine-6-carboxamide

: 76-05-1
trifluoroacetic acid

: tert-butyl 5-amino-2-methylthio-4-(3-(2-(N-methylpiperazino)-ethanesulfonamido)-phenyl)-thieno[2,3-d]primidine-6-carboxamide trifluoroacetic acid salt

Guidance literature:: 1-methyl-piperazine; tert-butyl 5-amino-2-methylthio-4-(3-(vinylsulfonamido)-phenyl)-thieno[2,3-d]pyrimidine-6-carboxamide;

trifluoroacetic acid; In 1,4-dioxane; water;