C₁₂H₈ClFN₄O

Base Information

• Chemical Name: C₁₂H₈ClFN₄O
• CAS No.: 1372858-34-8
• Molecular Formula: C₁₂H₈ClFN₄O
• Molecular Weight: 278.673
• Mol file: 1372858-34-8.mol

Synonyms:C₁₂H₈ClFN₄O

Chemical Property of C₁₂H₈ClFN₄O

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₂H₈ClFN₄O

There total 3 articles about C₁₂H₈ClFN₄O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C12H10ClFN4O → C12H8ClFN4O (1372858-34-8)

Guidance literature:

With chloroamine-T; In tetrahydrofuran; water; at 65 ℃; for 4h;

DOI:10.1016/j.bmcl.2011.11.067

Reference yield:

6-Chloro-2-methyl-2H-pyridazin-3-one (10071-38-2) → C12H8ClFN4O (1372858-34-8)

Guidance literature:

Multi-step reaction with 3 steps

1: hydrazine hydrate / 2 h / 70 °C

2: ethanol / 1 h / Reflux

3: chloroamine-T / tetrahydrofuran; water / 4 h / 65 °C

With chloroamine-T; hydrazine hydrate; In tetrahydrofuran; ethanol; water;

DOI:10.1016/j.bmcl.2011.11.067

Reference yield:

C5H8N4O (1245898-36-5) → C12H8ClFN4O (1372858-34-8)

Guidance literature:

Multi-step reaction with 2 steps

1: ethanol / 1 h / Reflux

2: chloroamine-T / tetrahydrofuran; water / 4 h / 65 °C

With chloroamine-T; In tetrahydrofuran; ethanol; water;

DOI:10.1016/j.bmcl.2011.11.067

upstream raw materials:

6-Chloro-2-methyl-2H-pyridazin-3-one

C₅H₈N₄O

Downstream raw materials:

C₁₂H₈Br₂ClFN₄O

C₁₂H₇BrClFN₄O

C₂₃H₁₉ClFN₅O₂