Technology Process of 1,2-di-O-acetyl-3,4-di-O-benzyl-β-D-glucodialdehydo-1,5-pyranose
There total 7 articles about 1,2-di-O-acetyl-3,4-di-O-benzyl-β-D-glucodialdehydo-1,5-pyranose which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1: sodium methoxide / methanol / 12 h / 25 °C
2: diisopropylethylamine / dimethylformamide / 24 h / 25 °C
3: 1.) sodium hydride / 1.) glyme, 0 deg C, 30 min, 2.) glyme, 25 deg C, 24 h
4: 1.5 h / Ambient temperature
5: 95 percent / silica gel / benzene / 18 h / Ambient temperature
6: 1.) N-chlorosuccinimide, dimethyl sulfide, 2.) triethylamine / 1.) toluene, -20 deg C, 4 h, 2.) toluene, from -20 deg C to RT
With
N-chloro-succinimide; dimethylsulfide; sodium methylate; silica gel; sodium hydride; triethylamine; N-ethyl-N,N-diisopropylamine;
In
methanol; N,N-dimethyl-formamide; benzene;
DOI:10.1021/jo00350a073
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) sodium hydride / 1.) glyme, 0 deg C, 30 min, 2.) glyme, 25 deg C, 24 h
2: 1.5 h / Ambient temperature
3: 95 percent / silica gel / benzene / 18 h / Ambient temperature
4: 1.) N-chlorosuccinimide, dimethyl sulfide, 2.) triethylamine / 1.) toluene, -20 deg C, 4 h, 2.) toluene, from -20 deg C to RT
With
N-chloro-succinimide; dimethylsulfide; silica gel; sodium hydride; triethylamine;
In
benzene;
DOI:10.1021/jo00350a073
- Guidance literature:
-
Multi-step reaction with 5 steps
1: diisopropylethylamine / dimethylformamide / 24 h / 25 °C
2: 1.) sodium hydride / 1.) glyme, 0 deg C, 30 min, 2.) glyme, 25 deg C, 24 h
3: 1.5 h / Ambient temperature
4: 95 percent / silica gel / benzene / 18 h / Ambient temperature
5: 1.) N-chlorosuccinimide, dimethyl sulfide, 2.) triethylamine / 1.) toluene, -20 deg C, 4 h, 2.) toluene, from -20 deg C to RT
With
N-chloro-succinimide; dimethylsulfide; silica gel; sodium hydride; triethylamine; N-ethyl-N,N-diisopropylamine;
In
N,N-dimethyl-formamide; benzene;
DOI:10.1021/jo00350a073
