Technology Process of C26H27F3N2O5S
There total 5 articles about C26H27F3N2O5S which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: sodium hydride / N,N-dimethyl-formamide / 0 - 20 °C
2: tris-(dibenzylideneacetone)dipalladium(0); caesium carbonate; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene / toluene / Reflux
With
tris-(dibenzylideneacetone)dipalladium(0); sodium hydride; caesium carbonate; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene;
In
N,N-dimethyl-formamide; toluene;
DOI:10.1016/j.bmcl.2012.01.022
- Guidance literature:
-
Multi-step reaction with 3 steps
1: potassium carbonate / water; isopropyl alcohol / 0 - 20 °C
2: sodium hydride / N,N-dimethyl-formamide / 0 - 20 °C
3: tris-(dibenzylideneacetone)dipalladium(0); caesium carbonate; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene / toluene / Reflux
With
tris-(dibenzylideneacetone)dipalladium(0); sodium hydride; potassium carbonate; caesium carbonate; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene;
In
water; N,N-dimethyl-formamide; isopropyl alcohol; toluene;
DOI:10.1016/j.bmcl.2012.01.022
- Guidance literature:
-
Multi-step reaction with 4 steps
1: hydrogenchloride / ethanol; water / Reflux
2: potassium carbonate / water; isopropyl alcohol / 0 - 20 °C
3: sodium hydride / N,N-dimethyl-formamide / 0 - 20 °C
4: tris-(dibenzylideneacetone)dipalladium(0); caesium carbonate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene / toluene / Reflux
With
hydrogenchloride; tris-(dibenzylideneacetone)dipalladium(0); sodium hydride; potassium carbonate; caesium carbonate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene;
In
ethanol; water; N,N-dimethyl-formamide; isopropyl alcohol; toluene;
1: Fischer indole cyclization;
DOI:10.1016/j.bmcl.2012.01.022