(R,R)-1,2-dicyclohexylethane-1,2-diol (1R)-(dimethylphenylsilyl)-[1-2H,3H]methylboronate

Base Information

Chemical Name:(R,R)-1,2-dicyclohexylethane-1,2-diol (1R)-(dimethylphenylsilyl)-[1-2H,3H]methylboronate
CAS No.:869218-71-3
Molecular Formula:C₂₃H₃₇BO₂Si
Molecular Weight:387.426
Hs Code.:

Synonyms:(R,R)-1,2-dicyclohexylethane-1,2-diol (1R)-(dimethylphenylsilyl)-[1-2H,3H]methylboronate

Suppliers and Price of (R,R)-1,2-dicyclohexylethane-1,2-diol (1R)-(dimethylphenylsilyl)-[1-2H,3H]methylboronate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (R,R)-1,2-dicyclohexylethane-1,2-diol (1R)-(dimethylphenylsilyl)-[1-2H,3H]methylboronate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R,R)-1,2-dicyclohexylethane-1,2-diol (1R)-(dimethylphenylsilyl)-[1-2H,3H]methylboronate

There total 11 articles about (R,R)-1,2-dicyclohexylethane-1,2-diol (1R)-(dimethylphenylsilyl)-[1-2H,3H]methylboronate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 869218-70-2
(R,R)-1,2-dicyclohexylethane-1,2-diol {(1R)-[(S,S)-N,N-bis(1-phenylethyl)carbamoyloxy](dimethylphenylsilyl)[1-2H]methyl}boronate

: LiBEt₃T

: 869218-71-3
(R,R)-1,2-dicyclohexylethane-1,2-diol (1R)-(dimethylphenylsilyl)-[1-2H,3H]methylboronate

Guidance literature:: In not given;
DOI:10.1021/ja051568g

Reference yield:

: 869218-52-0
(R,R)-1,2-dicyclohexylethane-1,2-diol tert-butyl alcohol borate

: 869218-71-3
(R,R)-1,2-dicyclohexylethane-1,2-diol (1R)-(dimethylphenylsilyl)-[1-2H,3H]methylboronate

Guidance literature:: Multi-step reaction with 2 steps

1.1: s-BuLi; TMEDA / tetrahydrofuran; cyclohexane / 0.25 h / -78 °C

1.2: 32 percent / tetrahydrofuran; cyclohexane / -78 °C

2.1: LiBEt₃T / diethyl ether / 0 °C

With LiBEt₃T; N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; In tetrahydrofuran; diethyl ether; cyclohexane;
DOI:10.1021/ja051568g

Reference yield:

: 869218-63-3
(S)-pinanediol (dimethylphenylsilyl)methylboronate

: 869218-71-3
(R,R)-1,2-dicyclohexylethane-1,2-diol (1R)-(dimethylphenylsilyl)-[1-2H,3H]methylboronate

Guidance literature:: Multi-step reaction with 5 steps

1.1: aq. H₂O₂; NaHCO₃ / tetrahydrofuran / 50 °C

1.2: 78 percent / pentaerythritol / tetrahydrofuran; H₂O

2.1: 4.92 g / DMAP / toluene / Heating

3.1: s-BuLi; TMEDA / tetrahydrofuran; cyclohexane / 0.17 h / -78 °C

3.2: 92 percent / D₂O / tetrahydrofuran; cyclohexane / 15 h / -78 °C

4.1: s-BuLi; TMEDA / tetrahydrofuran; cyclohexane / 0.25 h / -78 °C

4.2: 32 percent / tetrahydrofuran; cyclohexane / -78 °C

5.1: LiBEt₃T / diethyl ether / 0 °C

With dmap; LiBEt₃T; N,N,N,N,-tetramethylethylenediamine; dihydrogen peroxide; sec.-butyllithium; sodium hydrogencarbonate; In tetrahydrofuran; diethyl ether; cyclohexane; toluene;
DOI:10.1021/ja051568g