triclosan-β-D-galactopyranoside

Base Information

• Chemical Name: triclosan-β-D-galactopyranoside
• CAS No.: 1615248-67-3
• Molecular Formula: C₁₈H₁₇Cl₃O₇
• Molecular Weight: 451.688
• Mol file: 1615248-67-3.mol

Synonyms:triclosan-β-D-galactopyranoside

Chemical Property of triclosan-β-D-galactopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of triclosan-β-D-galactopyranoside

There total 3 articles about triclosan-β-D-galactopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-5-chloro-2-(2,4-dichlorophenoxy)phenol → triclosan-β-D-galactopyranoside (1615248-67-3)

Guidance literature:

With sodium methylate; In methanol; for 5h;

Reference yield:

triclosan (3380-34-5,88032-08-0) + 2,3,4,6-tetra-O-acetyl-D-galactopyranosyl trichloroacetimidate (74808-10-9,86520-63-0,87119-53-7,92052-29-4,121238-27-5,142831-80-9,127061-80-7) → triclosan-β-D-galactopyranoside (1615248-67-3)

Guidance literature:

Multi-step reaction with 2 steps

1: boron trifluoride diethyl etherate / dichloromethane / 2 h

2: sodium methylate / methanol / 5 h

With boron trifluoride diethyl etherate; sodium methylate; In methanol; dichloromethane;

Reference yield:

triclosan (3380-34-5,88032-08-0) + 1-bromo-1-deoxy-2,3,4,6-tetra-O-acetyl-a-D-galactopyranoside (3068-32-4) → triclosan-β-D-galactopyranoside (1615248-67-3)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydroxide / water; acetone / 18 h / 20 °C

2: potassium carbonate / methanol / 20 °C

With potassium carbonate; sodium hydroxide; In methanol; water; acetone;

DOI:10.1016/j.ejmech.2018.10.053

upstream raw materials:

triclosan

2,3,4,6-tetra-O-acetyl-D-galactopyranosyl trichloroacetimidate

1-bromo-1-deoxy-2,3,4,6-tetra-O-acetyl-a-D-galactopyranoside