(2R,3R,5E,9Z)-2,3,6,10-tetramethyl-5,9-dodecadien-1-ol tosylate

Base Information

• Chemical Name: (2R,3R,5E,9Z)-2,3,6,10-tetramethyl-5,9-dodecadien-1-ol tosylate
• CAS No.: 78094-77-6
• Molecular Formula: C₂₃H₃₆O₃S
• Molecular Weight: 392.603
• Mol file: 78094-77-6.mol

Synonyms:(2R,3R,5E,9Z)-2,3,6,10-tetramethyl-5,9-dodecadien-1-ol tosylate

Chemical Property of (2R,3R,5E,9Z)-2,3,6,10-tetramethyl-5,9-dodecadien-1-ol tosylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2R,3R,5E,9Z)-2,3,6,10-tetramethyl-5,9-dodecadien-1-ol tosylate

There total 41 articles about (2R,3R,5E,9Z)-2,3,6,10-tetramethyl-5,9-dodecadien-1-ol tosylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

(2R,3R,5E,9Z)-2,3,6,10-tetramethyl-5,9-dodecadien-1-ol (78094-76-5) + p-toluenesulfonyl chloride (98-59-9) → (2R,3R,5E,9Z)-2,3,6,10-tetramethyl-5,9-dodecadien-1-ol tosylate (78094-77-6)

Guidance literature:

In pyridine;

DOI:10.1016/0040-4039(81)80126-8

Reference yield: 90.0%

(2R*,3R*,5E,9Z)-2,3,6,10-tetramethyl-5,9-dodecadien-1-ol (78094-76-5,83339-00-8,83377-60-0) + p-toluenesulfonyl chloride (98-59-9) → (2R*,3R*,5E,9Z)-2,3,6,10-tetramethyl-5,9-dodecadien-1-ol tosylate (78094-77-6,83339-01-9,83377-61-1)

Guidance literature:

With C₆H₅N; at 0 - 5 ℃; overnight;

DOI:10.1016/0040-4020(82)85108-9

Reference yield:

(4EZ,9Z)-erythro-2,3,10-trimethyl-6-methylenedodeca-4,9-dien-1-ol → (2R*,3R*,5E,9Z)-2,3,6,10-tetramethyl-5,9-dodecadien-1-ol tosylate (78094-77-6,83339-01-9,83377-61-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 76 percent / H2 / (ν⁶-naphthalene)tricarbonylchromium / tetrahydrofuran / 3 h / 50 °C / 37503.8 Torr

2: pyridine / CH₂Cl₂

With pyridine; hydrogen; tricarbonyl(naphthalene)chromium⁽⁰⁾; In tetrahydrofuran; dichloromethane;

DOI:10.1039/b002343o

upstream raw materials:

(2R,3R,5E,9Z)-2,3,6,10-tetramethyl-5,9-dodecadien-1-ol

p-toluenesulfonyl chloride

(Z)-3-methyl-1-bromo-2-pentene

(4R^*,5R^*)-4,5-dimethyl-2-tetrahydropyranol