(1R)-1-(N-tert-butoxycarbonyl-L-O-methyltyrosyl-L-valyl)amino-2-phenylethylboronic acid (+)-pinanediol ester

Base Information

Chemical Name:(1R)-1-(N-tert-butoxycarbonyl-L-O-methyltyrosyl-L-valyl)amino-2-phenylethylboronic acid (+)-pinanediol ester
CAS No.:1158974-99-2
Molecular Formula:C₃₈H₅₄BN₃O₇
Molecular Weight:675.674
Hs Code.:

Synonyms:(1R)-1-(N-tert-butoxycarbonyl-L-O-methyltyrosyl-L-valyl)amino-2-phenylethylboronic acid (+)-pinanediol ester

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Chemical Property of (1R)-1-(N-tert-butoxycarbonyl-L-O-methyltyrosyl-L-valyl)amino-2-phenylethylboronic acid (+)-pinanediol ester

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Technology Process of (1R)-1-(N-tert-butoxycarbonyl-L-O-methyltyrosyl-L-valyl)amino-2-phenylethylboronic acid (+)-pinanediol ester

There total 1 articles about (1R)-1-(N-tert-butoxycarbonyl-L-O-methyltyrosyl-L-valyl)amino-2-phenylethylboronic acid (+)-pinanediol ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

: 1158974-97-0
Boc-Tyr(Me)-Val-OH

: 514820-49-6
(R)-2-phenyl-1-((3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)ethanamine 2,2,2-trifluoroacetate

: 1158974-99-2
(1R)-1-(N-tert-butoxycarbonyl-L-O-methyltyrosyl-L-valyl)amino-2-phenylethylboronic acid (+)-pinanediol ester

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 20h;
DOI:10.1016/j.bmcl.2009.02.117